Concept

Carotid ultrasonography

Publications associées (29)

Sub-micrometer morphology of human atherosclerotic plaque revealed by synchrotron radiation-based mu CT-A comparison with histology

Histology is a long standing and well-established gold standard for pathological characterizations. In recent years however, synchrotron radiation-based micro-computed tomography (SR mu CT) has become a tool for extending the imaging of two-dimensional thi ...

PUBLIC LIBRARY SCIENCE2022

A Proof of Concept for Computational Fluid Dynamic Analysis of the Left Atrium in Atrial Fibrillation on a Patient-Specific Basis

Alfio Quarteroni, Davide Forti, Filippo Menghini

Atrial fibrillation (AF) is associated with a fivefold increase in the risk of cerebrovascular events, being responsible of 15-18% of all strokes. The morphological and functional remodeling of the left atrium (LA) caused by AF favors blood stasis and, con ...

ASME2020

Photodynamic therapy for the treatment of atherosclerotic plaque: Lost in translation?

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Manish Jain

Acute coronary syndrome is a life-threatening condition of utmost clinical importance, which, despite recent progress in the field, is still associated with high morbidity and mortality. Acute coronary syndrome results from a rupture or erosion of vulnerab ...

Wiley2017

Assessment of shear stress related parameters in the carotid bifurcation using mouse-specific FSI simulations

Bram Trachet, Patrick Segers

The ApoE(-/-) mouse is a common small animal model to study atherosclerosis, an inflammatory disease of the large and medium sized arteries such as the carotid artery. It is generally accepted that the wall shear stress, induced by the blood flow, plays a ...

Elsevier Sci Ltd2016

Shear Stress Metrics and Their Relation to Atherosclerosis: An In Vivo Follow-up Study in Atherosclerotic Mice

Bram Trachet, Patrick Segers

It is generally accepted that low and oscillatory wall shear stress favors the initiation and development of atherosclerosis. However, a quantitative analysis of the association between shear stress metrics at baseline and lesion prevalence at a later stag ...

Springer Verlag2016

Pitfalls Of Doppler Measurements For Arterial Blood Flow Quantification In Small Animal Research: A Study Based On Virtual Ultrasound Imaging

Bram Trachet, Patrick Segers

High-resolution Doppler is a popular tool for evaluating cardiovascular physiology in mutant mice, though its 1-D nature and spectral broadening processes complicate interpretation of the measurement. Hence, it is crucial for pre-clinical researchers to kn ...

Elsevier2016

Visualization of hepatic arteries with 3D ultrasound during intra-arterial therapies

Anaïs Laure Marie-Thérèse Badoual, François Michaud, Alexandre Bigot

Liver cancer represents the second most common cause of cancer-related mortality worldwide. The prognosis is poor with an overall mortality of 95%. Moreover, most hepatic tumors are unresectable due to their advanced stage at discovery or poor underlying l ...

Spie-Int Soc Optical Engineering2016

Vulnerable Plaque Detection and Quantification with Gold Particle-Enhanced Computed Tomography in Atherosclerotic Mouse Models

Bram Trachet, Patrick Segers

Recently, an apolipoprotein E-deficient (ApoE(-/-)) mouse model with a mutation (C1039G+/-) in the fibrillin-1 (Fbn1) gene (ApoE(-/-)Fbn1(C1039G+/-) mouse model) was developed showing vulnerable atherosclerotic plaques, prone to rupture, in contrast to the ...

B C Decker Inc2015

Ultrafast laser ablation for targeted atherosclerotic plaque removal

Demetri Psaltis, Donald Benjaman Conkey, Thomas Jean Victor Marie Lanvin, Laurent Descloux

Coronary artery disease, the main cause of heart disease, develops as immune cells and lipids accumulate into plaques within the coronary arterial wall. As a plaque grows, the tissue layer (fibrous cap) separating it from the blood flow becomes thinner and ...

Spie-Int Soc Optical Engineering2015

Blood flow velocity field estimation via spatial regression with PDE penalization

Fabio Nobile

We propose an innovative method for the accurate estimation of surfaces and spatial fields when prior knowledge of the phenomenon under study is available. The prior knowledge included in the model derives from physics, physiology, or mechanics of the prob ...

American Statistical Association2015

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