Publications associées à Immunoprécipitation de chromatine

Principles of ChIP-seq Data Analysis Illustrated with Examples

Giovanna Ambrosini, Philipp Bucher, René Dreos

Chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-seq) is a powerful method to determine how transcription factors and other chromatin-associated proteins interact with DNA in order to regulate gene transcription. A single C ...

Copicentro Granada S L2014

Identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data

Bart Deplancke, Sebastian Martin Waszak, Sunil Kumar Raghav, Nouria Hernandez, Alisa Yurovsky

Motivation: High-throughput sequencing technologies enable the genome-wide analysis of the impact of genetic variation on molecular phenotypes at unprecedented resolution. However, although powerful, these technologies can also introduce unexpected artifac ...

Oxford University Press2014

The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis

Stewart Cole, Jacques Rougemont, Claudia Sala, Andrej Benjak, Swapna Uplekar

The PhoPR two-component system is essential for virulence in Mycobacterium tuberculosis where it controls expression of approximately 2% of the genes, including those for the ESX-1 secretion apparatus, a major virulence determinant. Mutations in phoP lead ...

Public Library of Science2014

Engineering chromatin states: Chemical and synthetic biology approaches to investigate histone modification function

Beat Fierz, Horst Pick, Sinan Kilic

Patterns of histone post-translational modifications (PTMs) and DNA modifications establish a landscape of chromatin states with regulatory impact on gene expression, cell differentiation and development. These diverse modifications are read out by effecto ...

Elsevier Science Bv2014

Characteristic bimodal profiles of RNA polymerase II at thousands of active mammalian promoters

Felix Naef, Cédric Gobet, Kyle Gustafson, Mathieu Quinodoz

Background: In mammals, ChIP-seq studies of RNA polymerase II (PolII) occupancy have been performed to reveal how recruitment, initiation and pausing of PolII may control transcription rates, but the focus is rarely on obtaining finely resolved profiles th ...

BioMed Central2014

Models that include supercoiling of topological domains reproduce several known features of interphase chromosomes

Julien Dorier, Yannis Burnier, Fabrizio Benedetti, Andrzej Stasiak

Understanding the structure of interphase chromosomes is essential to elucidate regulatory mechanisms of gene expression. During recent years, high-throughput DNA sequencing expanded the power of chromosome conformation capture (3C) methods that provide in ...

Oxford University Press2014

High-resolution detection of DNA binding sites of the global transcriptional regulator GlxR in Corynebacterium glutamicum

Stewart Cole, Claudia Sala, Swapna Uplekar

The transcriptional regulator GlxR has been characterized as a global hub within the gene-regulatory network of Corynebacterium glutamicum. Chromatin immunoprecipitation with a specific anti-GlxR antibody and subsequent high-throughput sequencing (ChIP-seq ...

Soc General Microbiology2013

Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein

Stewart Cole, Jacques Rougemont, Florence Pojer, Claudia Sala, Ruben Hartkoorn, Swapna Uplekar, Jeffrey Chen, Benjamin Blasco

The principal virulence determinant of Mycobacterium tuberculosis (Mtb), the ESX-1 protein secretion system, is positively controlled at the transcriptional level by EspR. Depletion of EspR reportedly affects a small number of genes, both positively or neg ...

Public Library of Science2012

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Immunoprécipitation de chromatine

Principles of ChIP-seq Data Analysis Illustrated with Examples

Identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data

The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis

Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy

Engineering chromatin states: Chemical and synthetic biology approaches to investigate histone modification function

Characteristic bimodal profiles of RNA polymerase II at thousands of active mammalian promoters

Models that include supercoiling of topological domains reproduce several known features of interphase chromosomes

High-resolution detection of DNA binding sites of the global transcriptional regulator GlxR in Corynebacterium glutamicum

RNA-Protein interactions at AU-rich elements

Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein

Graph Chatbot

Chattez avec Graph Search

RNA-Protein interactions at AU-rich elements

Characteristic bimodal profiles of RNA polymerase II at thousands of active mammalian promoters

Principles of ChIP-seq Data Analysis Illustrated with Examples

Engineering chromatin states: Chemical and synthetic biology approaches to investigate histone modification function

Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein

Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy

The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis

High-resolution detection of DNA binding sites of the global transcriptional regulator GlxR in Corynebacterium glutamicum

Models that include supercoiling of topological domains reproduce several known features of interphase chromosomes

Identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data