Publications associées à Réseau locomoteur spinal

A Computational Model for Epidural Electrical Stimulation of Spinal Sensorimotor Circuits

Silvestro Micera, Grégoire Courtine, Marco Capogrosso, Stanisa Raspopovic, Pavel Musienko, Nikolaus Wenger, Janine Beauparlant

Epidural electrical stimulation (EES) of lumbosacral segments can restore a range of movements after spinal cord injury. However, the mechanisms and neural structures through which EES facilitates movement execution remain unclear. Here, we designed a comp ...

Society for Neuroscience2013

Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro

Henry Markram, Vincent Delattre, Julie Meystre, Deborah La Mendola, Kamila Markram

Neuroligins (Nlgns) are postsynaptic cell adhesion molecules that form transynaptic complexes with presynaptic neurexins and regulate synapse maturation and plasticity. We studied the impact of the loss of Nlgn4 on the excitatory and inhibitory circuits in ...

Nature Publishing Group2013

Network Self-Organization Explains the Statistics and Dynamics of Synaptic Connection Strengths in Cortex

Christos Dimitrakakis

The information processing abilities of neural circuits arise from their synaptic connection patterns. Understanding the laws governing these connectivity patterns is essential for understanding brain function. The overall distribution of synaptic strength ...

Public Library Science2013

Spinal and Supraspinal Control of the Direction of Stepping during Locomotion

Pavel Musienko

Most bipeds and quadrupeds, in addition to forward walking, are also capable of backward and sideward walking. The direction of walking is determined by the direction of stepping movements of individual limbs in relation to the front-to-rear body axis. Our ...

Society for Neuroscience2012

Versatile robotic interface to evaluate, enable and train locomotion and balance after neuromotor disorders

Grégoire Courtine, Pavel Musienko, Rubia van den Brand, Lucia Florinda Friedli Wittler

Central nervous system (CNS) disorders distinctly impair locomotor pattern generation and balance, but technical limitations prevent independent assessment and rehabilitation of these subfunctions. Here we introduce a versatile robotic interface to evaluat ...

Nature Publishing Group2012

Thalamic control of cortical states

Carl Petersen, Sylvain Crochet, James Poulet

We investigated the impact of thalamus on ongoing cortical activity in the awake, behaving mouse. We demonstrate that the desynchronized cortical state during active behavior is driven by a centrally generated increase in thalamic action potential firing, ...

Nature Publishing Group2012

Multi-system neurorehabilitative strategies to restore motor functions following severe spinal cord injury

Grégoire Courtine, Pavel Musienko, Rubia van den Brand, Lucia Florinda Friedli Wittler

Severe spinal cord injury (SCI) permanently abolishes motor functions caudal to the lesion. However, the neuronal machinery sufficient to produce standing and stepping is located below most SCI, and can be reactivated with training. Therefore, why do rats ...

2012

The timing of exploratory decision-making revealed by single-trial topographic EEG analyses

José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano, Nicolas Bourdaud, Micah Murray, Athina Tzovara

Decision-making in an uncertain environment is driven by two major needs: exploring the environment to gather information or exploiting acquired knowledge to maximize reward. The neural processes underlying exploratory decision-making have been mainly stud ...

Elsevier2012

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Réseau locomoteur spinal

A Computational Model for Epidural Electrical Stimulation of Spinal Sensorimotor Circuits

Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro

Network Self-Organization Explains the Statistics and Dynamics of Synaptic Connection Strengths in Cortex

Proprioceptive Coupling within Motor Neurons Drives C. elegans Forward Locomotion

Spinal and Supraspinal Control of the Direction of Stepping during Locomotion

Somatosensory control of balance during locomotion in decerebrated cat

Versatile robotic interface to evaluate, enable and train locomotion and balance after neuromotor disorders

Thalamic control of cortical states

Multi-system neurorehabilitative strategies to restore motor functions following severe spinal cord injury

The timing of exploratory decision-making revealed by single-trial topographic EEG analyses

Graph Chatbot

Chattez avec Graph Search

Versatile robotic interface to evaluate, enable and train locomotion and balance after neuromotor disorders

Proprioceptive Coupling within Motor Neurons Drives C. elegans Forward Locomotion

Spinal and Supraspinal Control of the Direction of Stepping during Locomotion

Somatosensory control of balance during locomotion in decerebrated cat

Network Self-Organization Explains the Statistics and Dynamics of Synaptic Connection Strengths in Cortex

A Computational Model for Epidural Electrical Stimulation of Spinal Sensorimotor Circuits

The timing of exploratory decision-making revealed by single-trial topographic EEG analyses

Multi-system neurorehabilitative strategies to restore motor functions following severe spinal cord injury

Thalamic control of cortical states