Publications associées à Antimicrobial properties of copper

Multimodal Response to Copper Binding in Superoxide Dismutase Dynamics

Copper/zinc superoxide dismutase (SOD) is a homodimeric metalloenzyme that has been extensively studied as a benchmark for structure-function relationships in proteins, in particular because of its implication in the familial form of the neurodegenerative ...

AMER CHEMICAL SOC2020

New antimicrobial surfaces and intravascular catheters for the prevention of healthcare-associated infections

Myriam Koumba Sarah Ballo

Healthcare-associated infections (HAIs) are an important health issue around the world. The consequences of HAIs incidence include prolonged hospital stays, increased resistance of microorganisms to antimicrobials, higher costs for health systems and for t ...

EPFL2017

Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by -Secretase and Amyloid- Peptide Production

Patrick Fraering, Mitko Dimitrov, Hermeto Gerber, Guillermo Miguel Garcia Osuna

Recent evidence suggests involvement of biometal homeostasis in the pathological mechanisms in Alzheimer's disease (AD). For example, increased intracellular copper or zinc has been linked to a reduction in secreted levels of the AD-causing amyloid- peptid ...

Amer Soc Biochemistry Molecular Biology Inc2017

Bactericidal activity and mechanism of action of copper-sputtered flexible surfaces against multidrug-resistant pathogens

César Pulgarin, Juan Kiwi, Sami Rtimi, Myriam Koumba Sarah Ballo

Using direct current magnetron sputtering (DCMS), we generated flexible copper polyester surfaces (Cu-PES) and investigated their antimicrobial activity against a range of multidrug-resistant (MDR) pathogens including eight Gram-positive isolates (three me ...

Springer Verlag2016

Molecular dynamics simulations of apocupredoxins: insights into the formation and stabilization of copper sites under entatic control

Matteo Dal Peraro, Luciano Andres Abriata

Cupredoxins perform copper-mediated long-range electron transfer (ET) in biological systems. Their copper-binding sites have evolved to force copper ions into ET-competent systems with decreased reorganization energy, increased reduction potential, and a d ...

Springer2014

Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver

Kristin Schirmer, Laura Sigg, Renata Behra

Understanding mechanistic and cellular events underlying a toxicological outcome allows the prediction of impact of environmental stressors to organisms living in different habitats. A systems-based approach aids in characterizing molecular events, and the ...

National Academy of Sciences2014

Comparison of Methods for Evaluation of the Bactericidal Activity of Copper-Sputtered Surfaces against Methicillin-Resistant Staphylococcus aureus

César Pulgarin, Juan Kiwi

Bacteria can survive on hospital textiles and surfaces, from which they can be disseminated, representing a source of health care-associated infections (HCAIs). Surfaces containing copper (Cu), which is known for its bactericidal properties, could be an ef ...

American Society for Microbiology2012

Kondo-effect of substitutional cobalt impurities at copper surfaces

Klaus Kern, Peter Wahl

The influence of the coordination on the Kondo temperature of a magnetic impurity at a noble metal surface and the line shape observed in low temperature scanning tunneling spectroscopy (STS) is investigated for single cobalt atoms adsorbed on and embedded ...

2009