Concept
Éthambutol
Publications associées (4)
Monitoring Tuberculosis Drug Activity in Live Animals by Using Near-Infrared Fluorescence Imaging
Stewart Cole, Raphael Christopher Sommer
Worldwide, tuberculosis (TB) is the leading cause of death due to infection with a single pathogenic agent, Mycobacterium tuberculosis. In the absence of an effective vaccine, new, more powerful antibiotics are required to halt the growing spread of multid ...
AMER SOC MICROBIOLOGY2019GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis
Stewart Cole, Matteo Dal Peraro, Luciano Andres Abriata, Claudia Sala, Gaëlle Séraphine Kolly, Mahé Cécile Raccaud, Raju Mukherjee
Mycobacterium tuberculosis possesses a thick and highly hydrophobic cell wall principally composed of a mycolyl-arabinogalactan-peptidoglycan complex, which is critical for survival and virulence. DprE1 is a well-characterized component of decaprenyl-phosp ...
Amer Soc Microbiology2015Massive Gene Duplication Event among Clinical Isolates of the Mycobacterium tuberculosis W/Beijing Family
As part of our effort to uncover the molecular basis for the phenotypic variation among clinical Mycobacterium tuberculosis isolates, we have previously reported that isolates belonging to the W/Beijing lineage constitutively overexpress the DosR-regulated ...
2010