Concept

Arme chimique

Publications associées (85)

Chemical Developments in DNP-NMR

The Nuclear Magnetic Resonance (NMR) is an extraordinary tool to understand molecular structures. Its main limitation resides in its relatively low sensitivity when compared with other physico-chemical methods such as Mass Spectrometry (MS) or Optical Spec ...

EPFL2011

Flexible antibodies with nonprotein hinges

Florian Maria Wurm

There is a significant need for antibodies that can bind targets with greater affinity. Here we describe a. novel strategy employing chemical semisynthesis to produce symmetroadhesins: antibody-like molecules having nonprotein hinge regions that are more f ...

2011

Computational Design of Molecular Properties: Spotlight on Accuracy and Tuning

The Laboratory for Computational Molecular Design at ISIC devises original and accurate methodologies to establish, in silico, key structure property relationships of large chemical systems with particular emphasis on those associated with pi-conjugated fr ...

Schweizerische Chemische Gesellschaft2011

Tribocorrosion of stainless steel in sulfuric acid: Identification of corrosion-wear components and effect of contact area

Electrochemical and friction measurements during unidirectional sliding tests are used to monitor and to evaluate the tribocorrosion behavior of a passivating material. Tribocorrosion is the interplay between chemical, electrochemical, and mechanical proce ...

2010

An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries

Christoph Merten

Droplet-based microfluidic systems allow biological and chemical reactions to be performed on a drastically decreased scale. However, interfacing the outside world with such systems and generating high numbers of microdroplets of distinct chemical composit ...

2010

Recent knowledge and innovations related to hexofuranosides: structure, synthesis and applications

Ronan Euzen

Hexofuranosides are widely spread in nature, and notably in numerous pathogenic microorganisms. This particular five-membered ring for hexosides leads to novel biological properties and, as usual in glycochemistry, to completely different reactivity and se ...

2008

Growth parameters and shape specific synthesis of silicon nanowires by the VLS method

Cyril Cayron

In this paper the effect of varying temperature, pressure and chemical precursors on the vapour-liquid-solid (VLS) growth of silicon nanowires (Si NWs) have been investigated. Some aspects of nucleation and growth mechanisms are discussed. Control on Si NW ...

2008

Chemical approach for the study of the 'kissing complex' of Moloney murine leukaemia Virus

Sébastien Porcher

The replication of Moloney murine leukaemia virus relies on the formation of a stable homodimeric 'kissing complex' of a GACG tetraloop interacting through only two C center dot G base pairs flanked of 5'-adjacent Unpaired adenosines A9. Previous NMR inves ...

2008

Self-replicating hardware for reliability: The embryonics project

Daniel Mange, Joël Rossier, Pierre-André Mudry

The multicellular structure of biological organisms and the interpretation in each of their cells of a chemical program (the DNA string or genome) is the source of inspiration for the Embryonics (embryonic electronics) project, whose final objective is the ...

2007

Subgrid-scale modeling of reacting scalar fluxes in large-eddy simulations of atmospheric boundary layers

Fernando Porté Agel

In large-eddy simulations of atmospheric boundary layer turbulence, the lumped coefficient in the eddy-diffusion subgrid-scale (SGS) model is known to depend on scale for the case of inert scalars. This scale dependence is predominant near the surface. In ...

2006

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