Publications associées à Professional fitness coach

Transient vitamin B5 starving improves mammalian cell homeostasis and protein production

Maintaining a metabolic steady state is essential for an organism's fitness and survival when confronted with environmental stress, and metabolic imbalance can be reversed by exposing the organism to fasting. Here, we attempted to apply this physiological ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2020

The upper limit of cardiorespiratory fitness associated with longevity: an update

Johannes Burtscher

In 2013, mortality reductions with improving cardiorespiratory fitness (CRF) have been suggested to persist until 13 METs. More recently, accumulating evidence from large-scale studies suggests that mortality from all causes decreases with increasing CRF l ...

AMER INST MATHEMATICAL SCIENCES-AIMS2019

The fitness landscape of the codon space across environments

Jeffrey David Jensen, Claudia Bank, Sebastian Matuszewski

Fitness landscapes map the relationship between genotypes and fitness. However, most fitness landscape studies ignore the genetic architecture imposed by the codon table and thereby neglect the potential role of synonymous mutations. To quantify the fitnes ...

NATURE PUBLISHING GROUP2018

Resistance of echovirus 11 to ClO2 is associated with enhanced host receptor use, altered entry routes and high fitness

Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Jeffrey David Jensen, Qingxia Zhong, Hyunjin Shim

Waterborne viruses can exhibit resistance to common water disinfectants, yet the mechanisms that allow them to tolerate disinfection are poorly understood. Here, we generated echovirus 11 (E11) with resistance to chlorine dioxide (ClO2) by experimental evo ...

Amer Chemical Soc2017

The Seamless Peer and Cloud Evolution Framework

Dario Floreano, Joshua Evan Auerbach, Giovanni Iacca, Guillaume Paul Olivier Leclerc

Evolutionary algorithms are increasingly being applied to problems that are too computationally expensive to run on a single personal computer due to costly fitness function evaluations and/or large numbers of fitness evaluations. Here, we introduce the Se ...

ACM Press2016

On the (un) predictability of a large intragenic fitness landscape

Jeffrey David Jensen, Claudia Bank, Sebastian Matuszewski

The study of fitness landscapes, which aims at mapping genotypes to fitness, is receiving ever-increasing attention. Novel experimental approaches combined with next-generation sequencing (NGS) methods enable accurate and extensive studies of the fitness e ...

Natl Acad Sciences2016

Type 5 adenylyl cyclase disruption leads to enhanced exercise performance

Johan Auwerx, Laurent Mouchiroud, Richardus Houtkooper, Jie Zhang

The most important physiological mechanism mediating enhanced exercise performance is increased sympathetic, beta adrenergic receptor (beta-AR), and adenylyl cyclase (AC) activity. This is the first report of decreased AC activity mediating increased exerc ...

Wiley-Blackwell2015

A Systematic Survey of an Intragenic Epistatic Landscape

Jeffrey David Jensen, Claudia Bank

Mutations are the source of evolutionary variation. The interactions of multiple mutations can have important effects on fitness and evolutionary trajectories. We have recently described the distribution of fitness effects of all single mutations for a nin ...

Oxford Univ Press2015

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Professional fitness coach

The Effects of Spatial Organization and Fluid Flow on the Social Interactions in Microbial Communities

Transient vitamin B5 starving improves mammalian cell homeostasis and protein production

The upper limit of cardiorespiratory fitness associated with longevity: an update

The fitness landscape of the codon space across environments

Resistance of echovirus 11 to ClO2 is associated with enhanced host receptor use, altered entry routes and high fitness

The evolution of phenotypic plasticity under global change

The Seamless Peer and Cloud Evolution Framework

On the (un) predictability of a large intragenic fitness landscape

Type 5 adenylyl cyclase disruption leads to enhanced exercise performance

A Systematic Survey of an Intragenic Epistatic Landscape

Graph Chatbot

Chattez avec Graph Search

The Seamless Peer and Cloud Evolution Framework

A Systematic Survey of an Intragenic Epistatic Landscape

On the (un) predictability of a large intragenic fitness landscape

The fitness landscape of the codon space across environments

The Effects of Spatial Organization and Fluid Flow on the Social Interactions in Microbial Communities

Transient vitamin B5 starving improves mammalian cell homeostasis and protein production

Type 5 adenylyl cyclase disruption leads to enhanced exercise performance

The evolution of phenotypic plasticity under global change

The upper limit of cardiorespiratory fitness associated with longevity: an update

Resistance of echovirus 11 to ClO2 is associated with enhanced host receptor use, altered entry routes and high fitness