Publications associées à Alcohol and cancer

Tumor-educated Gr1+CD11b+cells drive breast cancer metastasis via OSM/IL-6/JAK-induced cancer cell plasticity

Nadine Fournier, Manon Bulliard, Annamaria Kauzlaric, Yu-Ting Huang, Rachel Marcone

Cancer cell plasticity contributes to therapy resistance and metastasis, which represent the main causes of cancer-related death, including in breast cancer. The tumor microenvironment drives cancer cell plasticity and metastasis, and unraveling the underl ...

Amer Soc Clinical Investigation Inc2024

Transposable elements mediate genetic effects altering the expression of nearby genes in colorectal cancer

Didier Trono, Evaristo Jose Planet Letschert, Nikolaos Lykoskoufis

Transposable elements (TEs) are prevalent repeats in the human genome, play a significant role in the regulome, and their disruption can contribute to tumorigenesis. However, TE influence on gene expression in cancer remains unclear. Here, we analyze 275 n ...

2024

Tumor dormancy: EMT beyond invasion and metastasis

Cathrin Brisken, Hazel Margaret Quinn, Patrik Aouad

More than two-thirds of cancer-related deaths are attributable to metastases. In some tumor types metastasis can occur up to 20 years after diagnosis and successful treatment of the primary tumor, a phenomenon termed late recurrence. Metastases arise from ...

WILEY2023

CellCharter reveals spatial cell niches associated with tissue remodeling and cell plasticity

Daniele Tavernari, Albert Santamaria Martinez, Giovanni Ciriello

Tissues are organized in cellular niches, the composition and interactions of which can be investigated using spatial omics technologies. However, systematic analyses of tissue composition are challenged by the scale and diversity of the data. Here we pres ...

Berlin2023

Non-genomic activation of the AKT-mTOR pathway by the mitochondrial stress response in thyroid cancer

Johan Auwerx, Kristina Schoonjans, Dongryeol Ryu

Cancer progression is associated with metabolic reprogramming and causes significant intracellular stress; however, the mechanisms that link cellular stress and growth signalling are not fully understood. Here, we identified a mechanism that couples the mi ...

SPRINGERNATURE2022

Hallmarks of Cancer: New Dimensions

Douglas Hanahan

The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity of cancer phenotypes and genotypes into a provisional set of underl y-ing principles. As knowledge of cancer mechanisms has progressed, other facets of the dis ...

AMER ASSOC CANCER RESEARCH2022

Association of neighbourhood disadvantage and individual socioeconomic position with all-cause mortality: a longitudinal multicohort analysis

Stéphane Joost, Idris Guessous

Background Few studies have examined the interactions between individual socioeconomic position and neighbourhood deprivation and the findings so far are heterogeneous. Using a large sample of diverse cohorts, we investigated the interaction effect of neig ...

ELSEVIER SCI LTD2022

Understanding Heavy Drinking at Night through Smartphone Sensing and Active Human Engagement

Daniel Gatica-Perez, Skanda Muralidhar, Thanh Trung Phan

Heavy alcohol consumption can lead to many severe consequences. In this paper, we study the phenomenon of heavy drinking at night (4+ drinks for women or 5+ for men on a single evening), using a smartphone sensing dataset depicting about nightlife and drin ...

ACM2020

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Alcohol and cancer

Tumor-educated Gr1+CD11b+cells drive breast cancer metastasis via OSM/IL-6/JAK-induced cancer cell plasticity

Transposable elements mediate genetic effects altering the expression of nearby genes in colorectal cancer

Unveiling breast cancer metastasis through an advanced X-ray imaging approach

Tumor dormancy: EMT beyond invasion and metastasis

CellCharter reveals spatial cell niches associated with tissue remodeling and cell plasticity

Non-genomic activation of the AKT-mTOR pathway by the mitochondrial stress response in thyroid cancer

Hallmarks of Cancer: New Dimensions

Association of neighbourhood disadvantage and individual socioeconomic position with all-cause mortality: a longitudinal multicohort analysis

Impaired cognitive flexibility and heightened urgency are associated with increased alcohol consumption in rodent models of excessive drinking

Understanding Heavy Drinking at Night through Smartphone Sensing and Active Human Engagement

Graph Chatbot

Chattez avec Graph Search

Tumor-educated Gr1+CD11b+cells drive breast cancer metastasis via OSM/IL-6/JAK-induced cancer cell plasticity

Transposable elements mediate genetic effects altering the expression of nearby genes in colorectal cancer

Unveiling breast cancer metastasis through an advanced X-ray imaging approach

Impaired cognitive flexibility and heightened urgency are associated with increased alcohol consumption in rodent models of excessive drinking

Non-genomic activation of the AKT-mTOR pathway by the mitochondrial stress response in thyroid cancer

Tumor dormancy: EMT beyond invasion and metastasis

Association of neighbourhood disadvantage and individual socioeconomic position with all-cause mortality: a longitudinal multicohort analysis

CellCharter reveals spatial cell niches associated with tissue remodeling and cell plasticity

Hallmarks of Cancer: New Dimensions

Understanding Heavy Drinking at Night through Smartphone Sensing and Active Human Engagement