Concept
Virus de la grippe A (H1N1)
Publications associées (37)
Antiviral Mechanism of Virucidal Sialic Acid Modified Cyclodextrin
Francesco Stellacci, Paulo Henrique Jacob Silva, Yong Zhu, Marine Batista, Andrey Sysoev
We have reported that CD-6'SLN [6-sialyllactosamine (6'SLN)-modified beta-cyclodextrin (CD)] can be a potential anti-influenza drug because it irreversibly deactivates virions. Indeed, in vivo, CD-6'SLN improved mice survival in an H1N1 infection model eve ...
MDPI2023Multivalent Virucidal Antivirals: Synthesis, Mechanisms of Action, and Immune-stimulating Effects
Viruses initiate invasion by binding to cell surface glycoproteins. Materials mimicking the carbohydrate motifs of these glycoproteins, such as heparan sulfate (HS) and sialic acid (SA) can block viral attachment and inhibit the infection. Multivalent disp ...
EPFL2023Expiratory Aerosol pH is a Driver of the Persistence of Airborne Influenza A Virus
To mitigate the spread of a viral disease, it is crucial to understand the factors that influence airborne virus transmission. However, the micro-environment to which the virus is exposed in expiratory aerosol particles is highly complex. The relative humi ...
SWISS CHEMICAL SOC2023Aerosol pH is an overlooked driver of airborne influenza and coronavirus inactivation
The current pandemic has added to the growing evidence that respiratory viruses can be transmitted by the airborne route. Non-pharmaceutical interventions, such as mask wearing or ventilation, aim to reduce the public health burden of respiratory diseases ...
2023Preliminary evidence that daily light exposure enhances the antibody response to influenza vaccination in patients with dementia
Enhancing lighting conditions in institutions for individuals with dementia improves their sleep, circadian rhythms and well-being. Here, we report first findings that exposure to brighter light during daytime may support the immune response to the annual ...
ELSEVIER2022Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load
Set-point viral load (SPVL), a common measure of human immunodeficiency virus (HIV)-1 virulence, is partially determined by viral genotype. Epidemiological evidence suggests that this viral property has been under stabilising selection, with a typical opti ...
OXFORD UNIV PRESS2022