Neuroleptique

Sciences sociales
Psychologie
Applied psychology
Psychologie clinique

Publications associées (30)

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Dynamic organization of human brain function and its relevance for psychosis vulnerability

Daniela Maria Zöller

The brain is the substrate of a complex dynamic system providing a remarkably varied range of functionalities, going from simple perception to higher-level cognition. Disturbances in its complex dynamics can cause an equally vast variety of mental disorder ...

EPFL2019

Mining the Potential of Label-Free Biosensors for In Vitro Antipsychotic Drug Screening

Sandro Carrara, Tugba Kilic, Hatice Altug, Maria Soler Aznar

The pharmaceutical industry is facing enormous challenges due to high drug attribution rates. For the past decades, novel methods have been developed for safety and efficacy testing, as well as for improving early development stages. In vitro screening met ...

2018

A novel psychoanalytical approach: An electrochemical ligand-binding assay to screen antipsychotics

Sandro Carrara, Tugba Kilic

Schizophrenia treatment may see a paradigm shift due to development of new atypical antipsychotic drugs (APDs), with better tolerability due to more selective dopamine (DA) receptor blockade. Monitoring of these APD candidates in biological fluids is of gr ...

2018

Cortical morphology development in patients with 22q11.2 deletion syndrome at ultra-high risk of psychosis

Maude Schneider, Marie Schaer, Daniela Maria Zöller, Maria Carmela Padula

Background. Patients with 22q11.2 deletion syndrome (22q11DS) present a high risk of developing psychosis. While clinical and cognitive predictors for the conversion towards a full-blown psychotic disorder are well defined and largely used in practice, neu ...

CAMBRIDGE UNIV PRESS2018

Sensorimotor Induction of Auditory Misattribution in Psychosis is Linked to Neural Disconnectivity

Olaf Blanke, Alessandra Griffa, Kim Do, Patric Hagmann, Andrea Serino, Roy Salomon, Giulio Rognini, Silvia Marchesotti, Pierre Progin

Background: Schneiderian first rank symptoms (FRS) are characterized by a diminished demarcation of self-other boundaries, causing misattribution of self-generated thoughts and actions to external sources. We have shown that introducing sensorimotor predic ...

2018

Inhaling xenon ameliorates l -dopa-induced dyskinesia in experimental parkinsonism

Grégoire Courtine, Eduardo Martin Moraud, Tomislav Milekovic, Shiqi Sun

Parkinson's disease motor symptoms are treated with levodopa, but long‐term treatment leads to disabling dyskinesia. Altered synaptic transmission and maladaptive plasticity of corticostriatal glutamatergic projections play a critical role in the pathophys ...

2018

Visual backward masking and the schizophrenia spectrum: EEG correlates

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Janir Nuno Ramos Antunes Da Cruz, Albulena Jashari-Shaqiri

Schizophrenia is a heterogeneous disease strongly influenced by genetic factors. We have previously shown that visual backward masking (VBM) is a very sensitive endophenotype of schizophrenia (Chkonia et al., 2010). Importantly, not only patients but also ...

2017

Influence of Facial Feedback and Mind Perception During a Cooperative Human-Robot Task in Schizophrenia

Aude Billard, Mahdi Khoramshahi, Laura Bénédicte Marine Cohen

Rapid progress in the area of humanoid robots offers tremendous possibilities for investigating and improving social competences in people with social deficits, but remains yet unexplored in schizophrenia. In this study, we examined the influence of social ...

Nature Research2017

Backward masking performance in patients with functional psychoses

Michael Herzog, Maya Roinishvili

In visual backward masking, a target is followed by a blank screen (ISI - Inter-stimulus-interval) and, then, a mask which deteriorates target processing. Schizophrenic patients show strong but complex processing deficits in visual masking compared to heal ...

2016

Association of PCK1 with Body Mass Index and Other Metabolic Features in Patients With Psychotropic Treatments

Pierre Magistretti, Aurélie Delacrétaz

Weight gain is a major health problem among psychiatric populations. It implicates several receptors and hormones involved in energy balance and metabolism. Phosphoenolpyruvate carboxykinase 1 is a rate-controlling enzyme involved in gluconeogenesis, glyce ...

Lippincott, Williams & Wilkins2015

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