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Publications associées (80)

Targeting molecular surfaces to engineer novel protein-based immunogens and inhibitors

Proteins are the basic building blocks necessary for the operation and regulation of virtually all functions in living organisms. Over millions of years, evolution has created a vast repertoire of proteins finely tuned to execute their biological functions ...

EPFL2022

Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae

Melanie Blokesch, David William Adams, Milena Jadwiga Jaskolska

Horizontal gene transfer can trigger rapid shifts in bacterial evolution. Driven by a variety of mobile genetic elements—in particular bacteriophages and plasmids—the ability to share genes within and across species underpins the exceptional adaptability o ...

2022

Protein Engineering for Personalized therapy and diagnosis

Lixia Wei

Protein Engineering, especially protein post-translational modification (PTM), ex-tends proteomes in a more complex way than one can expect from analysis of their encod-ing genomes. It can activate or deactivate certain catalytic functions, add new desired ...

EPFL2022

Projected resurgence of COVID-19 in the United States in July-December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination

Francisco Javier Perez Saez, Shi Chen

In Spring 2021, the highly transmissible SARS-CoV-2 Delta variant began to cause increases in cases, hospitalizations, and deaths in parts of the United States. At the time, with slowed vaccination uptake, this novel variant was expected to increase the ri ...

eLIFE SCIENCES PUBL LTD2022

Teaching under lockdown: the change in the social practice of teaching

Patrick Jermann, Roland John Tormey, Helena Kovacs

Due to the unprecedented situation caused by a global pandemic, the traditional way of teaching that is reliant on face-to-face interaction between teachers and students has been dismantled. This article looks into university teachers’ experiences of teach ...

Springer2022

The molecular treasure box of environmental Vibrio cholerae strains

Natalia Carolina Drebes Dorr

Cholera pandemics have been affecting humankind for centuries and are still considered a major public health problem, especially in regions around the world with poor access to clean water and sanitation. Cholera pandemics are caused by a specific lineage ...

EPFL2021

Interferon Lambda Delays the Emergence of Influenza Virus Resistance to Oseltamivir

Francesco Stellacci, Paulo Henrique Jacob Silva, Chiara Medaglia

Influenza viruses are a leading cause of morbidity and mortality worldwide. These air-borne pathogens are able to cross the species barrier, leading to regular seasonal epidemics and sporadic pandemics. Influenza viruses also possess a high genetic variabi ...

2021

Virucidal compositions and use thereof

Francesco Stellacci, Paulo Henrique Jacob Silva, Valeria Cagno, Özgün Kocabiyik

The invention relates to virucidal compositions comprising a sialic acid (SA) moiety, pharmaceutical compositions and disinfection and/or sterilization compositions comprising thereof and uses thereof in disinfection and/or sterilization methods and in tre ...

2021

Polyamide Nanofiber-Based Air Filters for Transparent Face Masks

Thierry Pelet, René M. Rossi

Transparent face masks are the ultimate solution for improving communication during pandemic times while at the same time slowing the spread of pathogens. Here, we demonstrate an easily scalable process consisting of directly electrospinning polyamide nano ...

AMER CHEMICAL SOC2021

Plunge and rebound of a taxi market through COVID-19 lockdown: Lessons learned from Shenzhen, China

Kenan Zhang

This paper traces the plunge and rebound of the taxi market in Shenzhen, China through the COVID-19 lockdown. A four-week taxi GPS trajectory data set is collected in the first quarter of 2020, which covers the period of lockdown and phased reopening in th ...

2021

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