Publications associées à Serum protein electrophoresis

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

Intracellular lipid droplets (LDs) can accumulate in response to inflammation, metabolic stresses, and other physiological/pathological processes. Herein, we investigated whether spike proteins of SARS-CoV-2 induce LDs in human peripheral blood mononuclear ...

Basel2023

Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework

Andrea Pfeifer, Florence Gauye, Tariq Afroz, Monisha Ratnam

Optimal pharmacokinetic (PK) properties of therapeutic monoclonal antibodies (mAbs) are essential to achieve the desired pharmacological benefits in patients. To accomplish this, we followed an approach comprising structure-based mAb charge engineering in ...

TAYLOR & FRANCIS INC2023

Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint

Davide Demurtas, Marc Moniatte, Adrian Schmid, Cyntia De Piano, Nikita Rudinskiy, Christophe Fuerer

Amyloid-beta (A beta) peptide oligomerization plays a central role in the pathogenesis of Alzheimer's disease (AD), and A beta oligomers are collectively considered an appealing therapeutic target for the treatment of AD. However, the molecular mechanisms ...

Elsevier Science Inc2016

Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fc gamma Receptor I

Arne Seitz, Romain Guiet, Duncan-Bruce Sutherland, Nicola Harris, Benjamin John Marsland, Beatrice Volpe, Julia Esser-von Bieren, Manuel Kulagin

Infections with intestinal helminths severely impact on human and veterinary health, particularly through the damage that these large parasites inflict when migrating through host tissues. Host immunity often targets the motility of tissue-migrating helmin ...

Amer Assoc Immunologists2015

Significance of surface charge and shell material of superparamagnetic iron oxide nanoparticle (SPION) based core/shell nanoparticles on the composition of the protein corona

Heinrich Hofmann, Lionel André Maurizi, Morteza Mahmoudi, Géraldine Sylvie Coullerez, Usawadee Sakulkhu

As nanoparticles (NPs) are increasingly used in many applications their safety and efficient applications in nanomedicine have become concerns. Protein coronas on nanomaterials' surfaces can influence how the cell "recognizes" nanoparticles, as well as the ...

Royal Soc Chemistry2015

Temperature-Controlled Masking/Unmasking of Cell-Adhesive Cues with Poly(ethylene glycol) Methacrylate Based Brushes

Harm-Anton Klok, Solenne Desseaux

Thin, thermoresponsive polymer coatings that allow to reversibly modulate cell adhesion and detachment are attractive substrates for cell sheet engineering. Usually, this is accomplished by applying thin poly(N-isopropylacrylamide) (PNIPAM) coatings, which ...

American Chemical Society2014

Compatible Buffer for Capillary Electrophoresis and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

Hubert Girault, Natalia Gasilova, Liang Qiao, Hong-Xu Chen

A compatible buffer system for the coupling of capillary electrophoresis (CE) with matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) was developed. The employed interface consists of a robot to drive a sliver-covered separation capil ...

Royal Society of Chemistry2013

Segmented Field OFFGEL® Electrophoresis

Hubert Girault, Julien Maillard, Fernando Cortes Salazar, Dmitry Momotenko, Elena Tobolkina

A multielectrode setup for protein OFFGEL electrophoresis that significantly improves protein separation efficiency has been developed. Here, the electric field is applied by segments between seven electrodes connected in series to six independent power su ...

Wiley-Blackwell2012

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Serum protein electrophoresis

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework

Telomere protection against oxidative stress

Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint

Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fc gamma Receptor I

Significance of surface charge and shell material of superparamagnetic iron oxide nanoparticle (SPION) based core/shell nanoparticles on the composition of the protein corona

Temperature-Controlled Masking/Unmasking of Cell-Adhesive Cues with Poly(ethylene glycol) Methacrylate Based Brushes

Compatible Buffer for Capillary Electrophoresis and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

Development of Electrokinetically Based Two-Dimensional Separation Methodologies for Proteomic Studies

Segmented Field OFFGEL® Electrophoresis

Graph Chatbot

Chattez avec Graph Search

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework

Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint

Temperature-Controlled Masking/Unmasking of Cell-Adhesive Cues with Poly(ethylene glycol) Methacrylate Based Brushes

Telomere protection against oxidative stress

Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fc gamma Receptor I

Significance of surface charge and shell material of superparamagnetic iron oxide nanoparticle (SPION) based core/shell nanoparticles on the composition of the protein corona

Compatible Buffer for Capillary Electrophoresis and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

Segmented Field OFFGEL® Electrophoresis

Development of Electrokinetically Based Two-Dimensional Separation Methodologies for Proteomic Studies