Concept
Transition épithélio-mésenchymateuse
Publications associées (187)
Deciphering the nature of cell state transitions in single cells using quantitative modeling of temporal dynamics
Cells are the smallest operational units of living systems. Through synthesis of various biomolecules and exchange of signals with the environment, cells tightly regulate their composition to realize a specific functional state. The transformation of a cel ...
EPFL2024Tumor dormancy: EMT beyond invasion and metastasis
Cathrin Brisken, Hazel Margaret Quinn, Patrik Aouad
More than two-thirds of cancer-related deaths are attributable to metastases. In some tumor types metastasis can occur up to 20 years after diagnosis and successful treatment of the primary tumor, a phenomenon termed late recurrence. Metastases arise from ...
WILEY2023Metabolic dependencies of metastasis-initiating cells in female breast cancer
Albert Santamaria Martinez, Pierre Vincent Dessen, Angela Madurga Alonso, Candice Megan T Young, Laurent Nam Ky Beziaud
Understanding the mechanisms that enable cancer cells to metastasize is essential in preventing cancer progression. Here we examine the metabolic adaptations of metastasis-initiating cells (MICs) in female breast cancer and how those shape their metastatic ...
Berlin2023Programming of Multicellular Patterning with Mechano-Chemically Microstructured Cell Niches
Multicellular patterning of stem-cell-derived tissue models is commonly achieved via self-organizing activities triggered by exogenous morphogenetic stimuli. However, such tissue models are prone to stochastic behavior, limiting the reproducibility of cell ...
WILEY2023