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Regulation of gene expression is essential for the functioning of all eukaryotic organisms. Understanding gene expression regulation requires determining which proteins interact with regulatory elements in chromatin. MS-based analysis of chromatin has emer ...
Human trajectory forecasting in crowds, at its core, is a sequence prediction problem with specific challenges of capturing inter-sequence dependencies (social interactions) and consequently predicting socially-compliant multimodal distributions. In recent ...
Background: Early prediction of symptoms and mortality risks for COVID-19 patients would improve healthcare outcomes, allow for the appropriate distribution of healthcare resources, reduce healthcare costs, aid in vaccine prioritization and self-isolation ...
BackgroundStatistical potentials, also named knowledge-based potentials, are scoring functions derived from empirical data that can be used to evaluate the quality of protein folds and protein-protein interaction (PPI) structures. In previous works we deco ...
BACKGROUND. Clinical Decision Support Systems (CDSS) are point-of-care questionnaires that guide consultations to evidence-based predictions with the aim of standardizing care and optimizing resource allocation. The data collected in these tools contain po ...
If one considers chemical-biology toolsets that have had the greatest impact on numerous fields of life sciences over the most recent years, proximity-labeling tools, such as APEX, and Bio-ID arguably lead the way. This article reflects upon the current st ...
Predicting the effects of mutations on protein stability is a key problem in fundamental and applied biology, still unsolved even for the relatively simple case of small, soluble, globular, monomeric, two-state-folder proteins. Many articles discuss the li ...
Proteins' biological functions are defined by the geometric and chemical structure of their 3D molecular surfaces. Recent works have shown that geometric deep learning can be used on mesh-based representations of proteins to identify potential functional s ...
The concept of post-tensioned glass beams builds on the concrete analogy of the reinforced glass beams. By additionally prestressing the reinforcement in a post-tensioned system, a compressive pre-stress is applied on the glass, enhancing the initial fract ...
Heat transfer measurements of flow boiling Carbon Dioxide (CO2) in vertical upward direction have been carried out with a dedicated test facility at the European Organization for Nuclear Research (CERN). The experiments have been conducted in a vertical up ...