Concept

Reticuloendothelial system

Publications associées (4)

Bioengineering approaches in immunotherapy

Vaccination has been regarded to as the most attractive immunotherapy for cancer because of its ability to instruct immune cells to recognize and kill tumor cells. Exosomes are one of the most recent discoveries translated from basic biology into experimen ...

EPFL2016

Development of a novel biomaterial for drug delivery

Anu Kodiyan

Gold nanoparticles (GNPs) are promising tools as drug delivery devices. However, upon intravenous injection, they aggregate and are rapidly eliminated from the systemic circulation by macrophages in the reticuloendothelial system, resulting in relatively s ...

2011

Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer

Michele De Palma, Ferdinando Pucci

Tumor-infiltrating myeloid cells, including tumor-associated macrophages (TAMs), have been implicated in tumor progression. We recently described a lineage of mouse monocytes characterized by expression of the Tie2 angiopoietin receptor and required for th ...

American Society of Hematology2007

Reversible immortalization of human primary cells by lentivector-mediated transfer of specific genes

Didier Trono

We exploited the ability of lentiviral vectors to govern the stable transduction of cells irrespective of their cycling status to induce the reversible immortalization of human primary cells. First, bicistronic HIV-derived lentiviral vectors expressing GFP ...

2000

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