Concept

Alcoolisme

Publications associées (34)

EEG signatures of schizophrenia: visual backward masking and microstates

Schizophrenia is a complex and devastating mental disorder that influences how one behaves, feels, and thinks. It affects a little less than 1 % of the world population and it is understood to be partly genetically mediated. Several genetic risk factors of ...

EPFL2019

DrinkSense: Characterizing Youth Drinking Behavior using Smartphones

Daniel Gatica-Perez, Darshan Santani

Alcohol consumption is the number one risk factor for morbidity and mortality among young people. In late adolescence and early adulthood, excessive drinking and intoxication are more common than in any other life period, increasing the risk of adverse phy ...

IEEE2018

After how many drinks does someone experience acute consequences-determining thresholds for binge drinking based on two event-level studies: Optimal thresholds for binge drinking

Background and Aims: The threshold of 4+/5+ drinks per occasion has been used for decades in alcohol research to distinguish between non risky versus risky episodic drinking. However, no study has assessed the validity of this threshold using event level ...

2018

What Reminds Young People That They Drank More Than Intended on Weekend Nights: An Event-Level Study

Objective: Young people often drink more alcohol than intended over the course of a night. This study investigates individual and night-specific factors predicting young people’s acknowledgment of having drunk more than intended. Method: Using the Yout ...

2018

GABA A receptors in the ventral tegmental area control the outcome of a social competition in rats

Maria del Carmen Sandi Perez, Michael van der Kooij, Ioannis Zalachoras

Social dominance can be attained through social competitions. Recent work in both humans and rodents has identified trait anxiety as a crucial predictor of social competitiveness. In addition, the anxiolytic GABAA positive modulator, diazepam, injected eit ...

2018

A preclinical model for identifying rats at risk of alcohol use disorder

Pierre Magistretti, Benjamin Boutrel

Alcohol use is one of the world's leading causes of death and disease, although only a small proportion of individuals develop persistent alcohol use disorder (AUD). The identification of vulnerable individuals prior to their chronic intoxication remains o ...

Springer Nature2017

NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

Stewart Cole

During active TB in humans a spectrum of pulmonary granulomas with central necrosis and hypoxia exists. BALB/c mice, predominantly used in TB drug development, do not reproduce this complex pathology thereby inaccurately predicting clinical outcome. We fou ...

Nature Publishing Group2017

Bayesian Uncertainty Management in Temporal Dependence of Extremes

Anthony Christopher Davison, Thomas Lugrin, Jonathan A. Tawn

Both marginal and dependence features must be described when modelling the extremes of a stationary time series. There are standard approaches to marginal modelling, but long- and short-range dependence of extremes may both appear. In applications, an assu ...

Springer Verlag2016

Bayesian uncertainty management in temporal dependence of extremes

Anthony Christopher Davison, Thomas Lugrin, Jonathan A. Tawn

Both marginal and dependence features must be described when modelling the extremes of a stationary time series. There are standard approaches to marginal modelling, but long-and short-range dependence of extremes may both appear. In applications, an assum ...

Springer Verlag2016

Cholinergic Signals in Mouse Barrel Cortex during Active Whisker Sensing

Carl Petersen, Sylvain Crochet, Yves Emile Alfred Kremer, Emmanuel Albert Eggermann

Internal brain states affect sensory perception, cognition, and learning. Many neocortical areas exhibit changes in the pattern and synchrony of neuronal activity during quiet versus active behaviors. Active behaviors are typically associated with desynchr ...

Elsevier2014

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