Trouble du comportement en sommeil paradoxal

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Biologie
Chronobiologie
Chronobiologie

Publications associées (28)

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A method for fast automated assessment of the magnetic resonance parkinsonism index

Bénédicte Marie Maréchal

In patients with parkinsonian syndromes, and particularly during the early stages of the clinical disease, differentiating between idiopathic Parkinson's disease and progressive supranuclear palsy is challenging. Imaging plays an important role in early di ...

SPRINGER2020

Pronounced α-synuclein pathology in a seeding-based mouse model is not sufficient to induce mitochondrial respiration deficits in the striatum and amygdala

Maria del Carmen Sandi Perez, Hilal Lashuel, Johannes Burtscher, Jean-Christophe Copin

Increasing evidence suggests that crosstalk between α-synuclein pathology formation and mitochondrial dysfunction plays a central role in the pathogenesis of Parkinson’s disease and related synucleinopathies. While mitochondrial dysfunction is a well-studi ...

2020

Object identity determines trans-saccadic integration

Michael Herzog, Leila Drissi Daoudi - Kleinbauer

Humans make two to four rapid eye movements (saccades) per second, which, surprisingly, does not lead to abrupt changes in vision. To the contrary, we perceive a stable world. Hence, an important question is how information is integrated across saccades. T ...

2020

Theory of intrinsic propagation losses in topological edge states of planar photonic crystals

Juan Pablo Vasco Cano

Using a semianalytic guided-mode expansion technique, we present theory and analysis of intrinsic propagation losses for topological photonic crystal slab waveguide structures with modified honeycomb lattices of circular or triangular holes. Although conve ...

AMER PHYSICAL SOC2020

Long-lasting feature integration

Leila Drissi Daoudi - Kleinbauer

In the classic model of vision, processing is local, feedforward and hierarchical. The first stages of the visual system are retinotopic, i.e., neighboring points in the outside world are mapped onto neighboring photoreceptors of the retina and this is pre ...

EPFL2020

Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau

Hilal Lashuel, Nadine Aït Bouziad, Anass Chiki, Galina Limorenko

The microtubule-associated protein Tau is implicated in the pathogenesis of several neurodegenerative disorders, including Alzheimer's disease. Increasing evidence suggests that post-translational modifications play critical roles in regulating Tau's norma ...

2020

Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons

Hasan Pezeshgi Modarres, Sha Li, Cyril Mikhail

Hypocretin/orexin (HCRT) and melanin concentrating hormone (MCH) neuropeptides are exclusively produced by the lateral hypothalamus and play important roles in sleep, metabolism, reward, and motivation. Loss of HCRT (ligands or receptors) causes the sleep ...

National Academy of Sciences2019

No Evidence for a Common Factor Underlying Visual Abilities in Healthy Older People

Michael Herzog, Aline Françoise Cretenoud, Aaron Michael Clarke, Albulena Jashari-Shaqiri

The world's population is aging at an increasing rate. Even in the absence of neurodegenerative disorders, healthy aging affects perception and cognition. In the context of cognition, common factors are well established. Much less is known about common fac ...

AMER PSYCHOLOGICAL ASSOC2019

Autophagy and LRRK2 in the Aging Brain

Salvatore Novello

Autophagy is a highly conserved process by which long-lived macromolecules, protein aggregates and dysfunctional/damaged organelles are delivered to lysosomes for degradation. Autophagy plays a crucial role in regulating protein quality control and cell ho ...

FRONTIERS MEDIA SA2019

Analysis of U-Shape Patterns in RR-Interval Time Series During Sleep

Jean-Marc Vesin, Grégoire Millet, Sasan Yazdani, Alexandre Thierry Robert Cherqui

The proposed study investigates a phenomenon, defined as "U-patterns", that takes place in the RR-interval time series during sleep. These patterns are defined as a U-shaped decrease-increase in the RR-intervals, with a duration of 20 to 40 seconds with a ...

IEEE2018

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Pronounced α-synuclein pathology in a seeding-based mouse model is not sufficient to induce mitochondrial respiration deficits in the striatum and amygdala

Maria del Carmen Sandi Perez, Hilal Lashuel, Johannes Burtscher, Jean-Christophe Copin

2020

Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau

Hilal Lashuel, Nadine Aït Bouziad, Anass Chiki, Galina Limorenko

2020