Concept
Organisme multicellulaire
Publications associées (131)
Climbing into their Skin to Understand Contextual Protein-Protein Associations and Localizations: Functional Investigations in Transgenic Live Model Organisms
Borrowing some quotes from Harper Lee's novel "To Kill A Mockingbird" to help frame our manuscript, we discuss methods to profile local proteomes. We initially focus on chemical biology regimens that function in live organisms and use reactive biotin speci ...
Wiley-V C H Verlag Gmbh2024Engineering hydrogel microenvironments for epithelial organoid culture
Organoids, miniature tissues generated from self-organizing stem cells within three-dimensional (3D) extracellular matrices (ECM), have opened up exciting possibilities for in vitro studies of complex physiological processes. A key factor in the success of ...
EPFL2024The nuclear-to-cytoplasmic ratio drives cellularization in the close animal relative Sphaeroforma arctica
Omaya Pierre Dudin, Marine Olivetta
The ratio of nuclear content to cytoplasmic volume (N/C ratio) is a key regulator driving the maternal-to -zy-gotic transition in most animal embryos. Altering this ratio often impacts zygotic genome activation and de-regulates the timing and outcome of em ...
CELL PRESS2023Programming of Multicellular Patterning with Mechano-Chemically Microstructured Cell Niches
Multicellular patterning of stem-cell-derived tissue models is commonly achieved via self-organizing activities triggered by exogenous morphogenetic stimuli. However, such tissue models are prone to stochastic behavior, limiting the reproducibility of cell ...
WILEY2023Industrial Biotechnology Conservation Processes: Similarities with Natural Long-Term Preservation of Biological Organisms
Corinne Scaletta, Philippe Abdel Sayed, Nathalie Hirt-Burri, Alexis Laurent
Cryopreservation and lyophilization processes are widely used for conservation purposes in the pharmaceutical, biotechnological, and food industries or in medical transplantation. Such processes deal with extremely low temperatures (e.g., -196 degrees C) a ...
MDPI2023Extensive programmed centriole elimination unveiled in C. elegans embryos
Centrioles are critical for fundamental cellular processes, including signaling, motility, and division. The extent to which centrioles are present after cell cycle exit in a developing organism is not known. The stereotypical lineage of Caenorhabditis ele ...
AMER ASSOC ADVANCEMENT SCIENCE2023Functional and structural characterization of polyphosphate-accumulating organisms in aerobic granular biofilms
The "Aerobic Granular Sludge" (AGS) technology for wastewater treatment is basedon dense microbial biofilm in the form of granular aggregates that have an excellentsettling property allowing high biomass concentrations in bioreactors. This promisingbiologi ...
EPFL2023