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The amyloid cascade hypothesis, supported by strong evidence from genetics, pathology and studies using animal models, implicates amyloid-beta (Abeta) oligomerization and fibrillogenesis as central causative events in the pathogenesis of Alzheimer's diseas ...
This research investigates new methods of designing folded plate structures that can be built with cross-laminated timber panels. Folded plate structures are attractive to both architects and engineers for their structural, spatial, and plastic qualities. ...
We introduce a nonradial potential term for coarse-grained (CG) molecular simulations of proteins. This term mimics the backbone dipole−dipole interactions and accounts for the needed directionality to form stable folded secondary structure elements. We sh ...
This book presents a refined methodology to predict fatigue life of high-strength steels: Uniform Material Law (UML) for High-Strength Steels. In contrast to other available methods, UML is a handy method as only tensile strength data of metals are needed ...
Richer and healthier agents tend to hold riskier portfolios and spend proportionally less on health expenditures. Potential explanations include health and wealth effects on preferences, expected longevity or disposable total wealth. Using HRS data, we per ...
This paper presents results of experimental investigations on the behaviour of GFRP pultruded profiles exposed to fire, in order to study the viability of their structural use in floors of buildings, taking into account the fulfilment of fire resistance re ...
The use of composites is growing in structural applications in many industries including aerospace, marine, wind turbine and civil engineering. There are uncertainties about the long term performance of these composites and how they will perform under cycl ...
We analyse the structural changes that have characterised the organisation of industrial R&D over the last 25 years. Taking Mowery's work (Industrial and Corporate Change, 2009, 18(1), 1-50) on the US as a starting point, we reconsider the different aspect ...
We investigate hypergraphic LP relaxations for the Steiner tree problem, primarily the partition LP relaxation introduced by Koenemann et al. [Math. Programming, 2009]. Specifically, we are interested in proving upper bounds on the integrality gap of this ...
The focus of this paper is on reducing the complexity in verification by exploiting modularity at various levels: in specification, in verification, and structurally. For specifications, we use the modular language CSP-OZ-DC, which allows us to decouple ve ...