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In the framework of spine traumatology, burst fractures are severe and are often caused by car accidents or by falls. The vertebra breaks under the traumatic compression and pieces of it are shattered in all directions. This type of fracture is often treat ...
In the United States approximately 50 million people suffer from low back pain. In the 20-50 years age group, this is the most important and expensive health care problem. The causes of low back pain are various. A herniated disk or spinal stenosis may tra ...
Large open surgical approaches are being extensively replaced by endoscopic and robotic techniques. Yet, these developments have not been paralleled by the necessary improvements in tissue adaptation, fusion or fixation. In order to advance the surgical ar ...
Severe lesions of the rodent or human spinal cord lead to permanent paralysis of the legs. Here, we review novel evidences suggesting that interventions combining pharmacological and electrical stimulations of the spinal cord have a high potential to promo ...
The project consists of: - mechanical tests of the prototype of the new implant and comparison to existing anterior fixation systems in a bone model material; - a literature review in order to classify the test results; - the development of a finite elemen ...
In this work we introduce and discuss several mathematical models, based on partial differential equations, devised to study the coupled transport of macromolecules as low-density lipoproteins in the blood stream and in the arterial walls. These models are ...
Changes in epidurally induced (S1) spinal cord reflexes were studied as a function of the level of restoration of stepping ability after spinal cord transection (ST). Three types of responses were observed. The early response (ER) had a latency of 2.5 to 3 ...
Many neurophysiological and behavioural studies suggested that the lower limb endpoint might be a centrally represented variable within the gravity reference frame and effectively controlled during the locomotion. This investigation examines the effects of ...
Lumbar puncture (LP) is performed by inserting a needle into the spinal canal to extract cerebrospinal fluid for diagnostic purposes. A virtual reality (VR) lumbar puncture simulator based on real patient data has been developed and evaluated. ...
Mutations in the gene encoding Cu/Zn superoxide dismutase (SOD1) underlie some familial cases of amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder characterized by loss of cortical, brainstem and spinal motoneurons. Transgenic mice over- ex ...