Concept
Breast cancer awareness
Publications associées (186)
Association between endocrine adjuvant therapy intake timing and disease-free survival in patients with high-risk early breast cancer: results of a sub-study of the UCBG- UNIRAD trial
Elise Hélène Dumas, Fabrice André
Background Circadian rhythms regulate cellular physiology and could in fl uence the ef fi cacy of endocrine therapy (ET) in breast cancer (BC). We prospectively tested this hypothesis within the UNIRAD adjuvant phase III trial (NCT01805271). Methods 1278 p ...
Elsevier2024Is There a Special Role for Ovarian Hormones in the Pathogenesis of Lobular Carcinoma?
Cathrin Brisken, Georgios Sflomos
Lobular carcinoma represent the most common special histological subtype of breast cancer, with the majority classed as hormone receptor positive. Rates of invasive lobular carcinoma in postmenopausal women have been seen to increase globally, while other ...
Endocrine Soc2024Unveiling breast cancer metastasis through an advanced X-ray imaging approach
Breast cancer is a significant global health burden, causing a substantial number of deaths. Systemic metastatic tumour cell dissemination is a major cause of poor outcomes. Understanding the mechanisms underlying metastasis is crucial for effective interv ...
Berlin2024Tumor-educated Gr1+CD11b+cells drive breast cancer metastasis via OSM/IL-6/JAK-induced cancer cell plasticity
Nadine Fournier, Manon Bulliard, Annamaria Kauzlaric, Yu-Ting Huang, Rachel Marcone
Cancer cell plasticity contributes to therapy resistance and metastasis, which represent the main causes of cancer-related death, including in breast cancer. The tumor microenvironment drives cancer cell plasticity and metastasis, and unraveling the underl ...
Amer Soc Clinical Investigation Inc2024Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy
Dendritic cells (DCs) are specialized myeloid cells with the ability to uptake, process, andpresent antigens to T lymphocytes. They also generate cytokine and chemokine gradients thatregulate immune cell trafficking, activation, and function. Monocyte-deri ...
EPFL2024The conceptual foundations of innate immunity: Taking stock 30 years later
While largely neglected over decades during which adaptive immunity captured most of the attention, innate immune mechanisms have now become central to our understanding of immunology. Innate immunity provides the first barrier to infection in vertebrates, ...
2024Optimized Modeling of Metastatic Triple-Negative Invasive Lobular Breast Carcinoma
Cathrin Brisken, Georgios Sflomos, Laura Battista
Simple Summary Invasive lobular carcinoma (ILC) is the second most common histologic subtype of breast cancer and is often detected at an advanced stage. Up to 30% of ILC cases relapse and present a challenge for treatment. Unfortunately, there are few mod ...
MDPI2023