Concept
Maladie respiratoire
Publications associées (169)
Inactivation mechanisms of influenza A virus under pH conditions encountered in aerosol particles as revealed by whole-virus HDX-MS
Athanasios Nenes, Tamar Kohn, Giovanni D'Angelo, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David, Walter Hugentobler, Jonathan Paz Montoya
Multiple respiratory viruses, including influenza A virus (IAV), can be transmitted via expiratory aerosol particles, and aerosol pH was recently identified as a major factor influencing airborne virus infectivity. Indoors, small exhaled aerosols undergo r ...
2023The neuraminidase activity of influenza A virus determines the strain-specific sensitivity to neutralization by respiratory mucus
Athanasios Nenes, Tamar Kohn, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David, Walter Hugentobler
Respiratory mucus lining the airway epithelium constitutes an important first line of defense against infection with influenza A virus (IAV). Previous studies suggested that the inhibitory potential of mucus relies not only on the presence of decoy recepto ...
2023Deep learning parametric response mapping from inspiratory chest CT scans: a new approach for small airway disease screening
Jiancheng Yang, Zhiye Wang, Jun Lu, Zhigang Li, Lin Qi, Ming Li, Bo Du, Yuxuan Sun, Ziyi Liu
Objectives Parametric response mapping (PRM) enables the evaluation of small airway disease (SAD) at the voxel level, but requires both inspiratory and expiratory chest CT scans. We hypothesize that deep learning PRM from inspiratory chest CT scans can eff ...
London2023Virtual reality intervention alleviates dyspnoea in patients recovering from COVID-19 pneumonia
Olaf Blanke, Bruno Herbelin, Florian Lance, Oliver Alan Kannape, Sylvain Cardin, Sophie Jacqueline Andrée Betka, Jemina Fasola, Aline Schmit
Background Immersive virtual reality (iVR)-based digital therapeutics are gaining clinical attention in the field of pain management. Based on known analogies between pain and dyspnoea, we investigated the effects of visual respiratory feedback on persiste ...
Sheffield2023ERS International Congress 2022: highlights from the Respiratory Clinical Care and Physiology Assembly
Sophie Jacqueline Andrée Betka
It is a challenge to keep abreast of all the clinical and scientific advances in the field of respiratory medicine. This article contains an overview of the laboratory-based science, clinical trials and qualitative research that were presented during the 2 ...
EUROPEAN RESPIRATORY SOC JOURNALS LTD2023Review on Uric Acid Recognition by MOFs with a Future in Machine Learning
Uric acid (UA) is produced from purine metabolism and serves as a prevalent biomarker for multiple diseases including cancer. Hyperuricemia or hypouricemia can cause multiple dysfunctions throughout the biological processes. Consequently, there is a pressi ...
Washington2023Identification of broad anti-coronavirus chemical agents for repurposing against SARS-CoV-2 and variants of concern
Gerardo Turcatti, Fabien Kuttler, Michael Bauer, Liliane Yang
Endemic human coronaviruses (hCoVs) 229E and OC43 cause respiratory disease with recurrent infections, while severe acute respiratory syndrome (SARS)-CoV-2 spreads across the world with impact on health and societies. Here, we report an image-based multicy ...
2022Balancing NAD(+) deficits with nicotinamide riboside: therapeutic possibilities and limitations
Alterations in cellular nicotinamide adenine dinucleotide (NAD(+)) levels have been observed in multiple lifestyle and age-related medical conditions. This has led to the hypothesis that dietary supplementation with NAD(+) precursors, or vitamin B3s, could ...
SPRINGER BASEL AG2022Breathing control, brain, and bodily self-consciousness: Toward immersive digiceuticals to alleviate respiratory suffering
Olaf Blanke, Sophie Jacqueline Andrée Betka
Breathing is peculiar among autonomic functions through several characteristics. It generates a very rich afferent traffic from an array of structures belonging to the respiratory system to various areas of the brain. It is intimately associated with bodil ...
2022