Concept
Hormone de libération de l'hormone de croissance
Publications associées (51)
Synthesis and biological evaluation of a cyclo-β-tetrapeptide as a somatostatin analog
Cyclo-beta-tetrapeptide I, a beta-peptidic analog of octreotide, was prepd. from beta-amino acid building blocks synthesized by Arndt-Eistert homologation of appropriately protected alpha-amino acids. The affinity of I for five different human somatostatin ...
1999Translational regulation of mRNAs with distinct IRE sequences by iron regulatory proteins 1 and 2
Iron regulatory proteins 1 and 2 (IRP-1, IRP-2) interact with iron-responsive elements (IREs) present in the 5'- or 3'-untranslated regions (UTR) of several mRNAs coding for proteins in iron metabolism. Whereas binding of IRP-1 and -2 to an IRE in the 5'-U ...
1998Strain mediated two-dimensional growth kinetics in metal heteroepitaxy: Ag/Pt(1111)
We have investigated the influence of strain on the morphology in metal heteroepitaxy at temperatures where growth is dominated by kinetics. Whereas Ag(111) homoepitaxy is three dimensional below 400 K, the growth of Ag On Pt(111) proceeds two dimensionall ...
1997A Fos-Jun element in the first intron of an alpha 2u-globulin gene
Johan Auwerx, Kristina Schoonjans
The hepatic expression of the alpha-2u-globulin gene family is controlled by a variety of hormones including steroids, growth hormone and insulin. The mechanisms by which these hormones affect alpha 2u-globulin expression are only partially understood. Rec ...
1993EXTENSION OF THE LAYER-BY-LAYER GROWTH REGIME OF INXGA1-XAS ON GAAS (001)
In order to delay the occurrence of the 2D-3D growth mode transition in highly strained InxGa1-xAs epitaxial layers grown on GaAs (001) by molecular beam epitaxy, the mass transport at the surface should be reduced. This can be achieved by increasing the g ...
1993Neonatal extinction of liver lipoprotein lipase expression
In contrast to the complete absence of lipoprotein lipase (LPL) mRNA in adult rat liver, fetal and neonatal rat liver contain substantial amounts of LPL mRNA, which is translated in active LPL protein as can be deduced from the presence of LPL activity in ...
1992Post-transcriptional regulation of the transferrin receptor and 4F2 antigen heavy chain mRNA during growth activation of spleen cells
The expression of several cell surface proteins including the transferrin receptor and 4F2 antigen is induced when quiescent cells are activated and proliferate. We have studied this induction in mouse spleen cells after stimulation with 4 beta-phorbol 12- ...
1991Involvement of second messengers in regulation of the low-density lipoprotein receptor gene
Transcription of the low-density lipoprotein receptor (LDL-R) gene in the human monocytic leukemic cell line THP-1 and in the human hepatocarcinoma cell line Hep-G2 is regulated by second messengers of the diacylglycerol-protein kinase C (DAG-PKC), inosito ...
1989Vitamin D status in the elderly: seasonal substrate deficiency causes 1,25-dihydroxycholecalciferol deficiency
The seasonal variation of 25-hydroxycholecalciferol and 1,25-dihydroxycholecalciferol was analyzed in 240 elderly subjects (mean age: 78 yr) in Belgium. Serum 25-hydroxycholecalciferol was lowest from February until May (mean levels less than 25 nmol/L). S ...
1987Actions of VIP, hGRF, PHI and secretin: comparative studies in cerebral cortex and adenohypophysis
Pierre Magistretti, Jean-Luc Martin
We have examined the effects of hGRF on cyclic AMP and glycogen levels in mouse cerebral cortical slices. hGRF-44-NH2 and hGRF-28-OH did not stimulate cyclic AMP formation nor glycogenolysis and did not antagonize the stimulatory effects of VIP on cyclic A ...
1986