Publications associées à Élément transposable

A yeast one-hybrid and microfluidics-based pipeline to map mammalian gene regulatory networks

Bart Deplancke, Sebastian Martin Waszak, Sunil Kumar Raghav, Alina Isakova, Jovan Simicevic, Jean-Daniel Feuz, Antonina Iagovitina

The comprehensive mapping of gene promoters and enhancers has significantly improved our understanding of how the mammalian regulatory genome is organized. An important challenge is to elucidate how these regulatory elements contribute to gene expression b ...

Nature / European Molecular Biology Organization2013

Learning Context Cues for Synapse Segmentation

Pascal Fua, Graham Knott, Carlos Joaquin Becker, Karim Ali

We present a new approach for the automated segmentation of synapses in image stacks acquired by Electron Microscopy (EM) that relies on image features specifically designed to take spatial context into account. These features are used to train a classifie ...

Institute of Electrical and Electronics Engineers2013

De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET

Didier Trono, Sonia Verp, Marc Samuel Friedli, Sandra Eloise Kjeldsen, Helen Mary Rowe

Endogenous retroviruses (ERVs) undergo de novo DNA methylation during the first few days of mammalian embryogenesis, although the factors that control the targeting of this process are largely unknown. We asked whether KAP1 (KRAB-associated protein 1) is i ...

Company Of Biologists Ltd2013

Shifting Fitness Landscapes In Response To Altered Environments

Jeffrey David Jensen, Claudia Bank

The role of adaptation in molecular evolution has been contentious for decades. Here, we shed light on the adaptive potential in Saccharomyces cerevisiae by presenting systematic fitness measurements for all possible point mutations in a region of Hsp90 un ...

Wiley-Blackwell2013

Discovering Regulators of Centriole Biogenesis through siRNA-Based Functional Genomics in Human Cells

Pierre Gönczy, Petr Strnad, Fernando Romero Balestra, Isabelle Fluckiger

Centrioles are essential for forming cilia, flagella, and centrosomes and are thus critical for a range of fundamental cellular processes. Despite their importance, the mechanisms governing centriole biogenesis remain incompletely understood. We performed ...

Cell Press2013

The Physiological Opportunism of Desulfitobacterium hafniense Strain TCE1 towards Organohalide Respiration with Tetrachloroethene

Christof Holliger, Julien Maillard, Aurélie Duret

Desulfitobacterium hafniense strain TCE1 is capable of metabolically reducing tetra- and trichloroethenes by organohalide respiration. A previous study revealed that the pce gene cluster responsible for this process is located on an active composite transp ...

American Society for Microbiology2012

RNA Profiling and Chromatin Immunoprecipitation-Sequencing Reveal that PTF1a Stabilizes Pancreas Progenitor Identity via the Control of MNX1/HLXB9 and a Network of Other Transcription Factors

Emilie Gesina, Philipp Bucher, Anne Grapin-Botton, Nancy Thompson

Pancreas development is initiated by the specification and expansion of a small group of endodermal cells. Several transcription factors are crucial for progenitor maintenance and expansion, but their interactions and the downstream targets mediating their ...

American Society for Microbiology2012

Genomic context analysis reveals dense interaction network between vertebrate ultraconserved non-coding elements

Philipp Bucher, Slavica Dimitrieva Janeva

Motivation: Genomic context analysis, also known as phylogenetic profiling, is widely used to infer functional interactions between proteins but rarely applied to non-coding cis-regulatory DNA elements. We were wondering whether this approach could provide ...

Oxford University Press2012

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Élément transposable

A yeast one-hybrid and microfluidics-based pipeline to map mammalian gene regulatory networks

Learning Context Cues for Synapse Segmentation

De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET

Shifting Fitness Landscapes In Response To Altered Environments

Opening a can of centipedes: New insights into mechanisms of body segmentation

Discovering Regulators of Centriole Biogenesis through siRNA-Based Functional Genomics in Human Cells

Discovering Regulators of Centriole Biogenesis through siRNA-Based Functional Genomics in Human Cells

The Physiological Opportunism of Desulfitobacterium hafniense Strain TCE1 towards Organohalide Respiration with Tetrachloroethene

RNA Profiling and Chromatin Immunoprecipitation-Sequencing Reveal that PTF1a Stabilizes Pancreas Progenitor Identity via the Control of MNX1/HLXB9 and a Network of Other Transcription Factors

Genomic context analysis reveals dense interaction network between vertebrate ultraconserved non-coding elements

Graph Chatbot

Chattez avec Graph Search

Genomic context analysis reveals dense interaction network between vertebrate ultraconserved non-coding elements

Opening a can of centipedes: New insights into mechanisms of body segmentation

Discovering Regulators of Centriole Biogenesis through siRNA-Based Functional Genomics in Human Cells

Shifting Fitness Landscapes In Response To Altered Environments

De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET

Discovering Regulators of Centriole Biogenesis through siRNA-Based Functional Genomics in Human Cells

RNA Profiling and Chromatin Immunoprecipitation-Sequencing Reveal that PTF1a Stabilizes Pancreas Progenitor Identity via the Control of MNX1/HLXB9 and a Network of Other Transcription Factors

The Physiological Opportunism of Desulfitobacterium hafniense Strain TCE1 towards Organohalide Respiration with Tetrachloroethene

A yeast one-hybrid and microfluidics-based pipeline to map mammalian gene regulatory networks

Learning Context Cues for Synapse Segmentation