Concept

Bronche

Publications associées (32)

Autofluorescence bronchoscopy: quantification of inter-patient variations of fluorescence intensity

Hubert van den Bergh, Georges Wagnières, Tanja Gabrecht, Blaise Lovisa

Autofluorescence (AF) from bronchial tissue is increasingly used for the endoscopic detection of early bronchial neoplasia. Several imaging systems are commercially available, all detecting the absolute or relative AF intensity and/or spectral contrasts be ...

Springer-Verlag2009

Postural adjustment in experimental leg length difference evaluated by means of thermal infrared imaging

Silvio Ionta

Limb length discrepancy (LLD) is defined as a condition in which limbs are unequal. The asymmetric load of body segments secondary to LLD may cause a tonic contraction of back and lower limb muscles, thus resulting in subtle cutaneous temperature variation ...

2009

Fetal-juvenile origins of point mutations in the adult human tracheal-bronchial epithelium: Absence of detectable effects of age, gender or smoking status

Stephan Morgenthaler, Per Olaf Ekstrom

Allele-specific mismatch amplification mutation assays (MAMA) of anatomically distinct sectors of the upper bronchial tracts of nine nonsmokers revealed many numerically dispersed clusters of the point mutations C742T, G746T, G747T of the TP53 gene, G35T o ...

2008

Autofluorescence detection of tumors in the human lung - spectroscopical measurements in situ, in an in vivo model and in vitro

Georges Wagnières, Tanja Gabrecht

To detect bronchial carcinoma by autofluorescence, we measured the spectra of tumor and normal tissue in situ, in an in vivo model and in vitro by fiber optic spectrometer and two-dimensional resolved microspectroscopy. The in situ measurements were perfor ...

Elsevier2008

Effects of dynamic compression on lentiviral transduction in an in vitro airway wall model

Melody Swartz, Alice Anna Tomei

Asthmatic patients are more susceptible to viral infection, and we asked whether dynamic strain on the airway wall (such as that associated with bronchoconstriction) would influence the rate of viral infection of the epithelial and subepithelial cells. To ...

2008

Optimized autofluorescence bronchoscopy using additional backscattered red light

Hubert van den Bergh, Georges Wagnières, Tanja Gabrecht

Autofluorescence bronchoscopy (AFB) has been shown to be a highly sensitive tool for the detection of early endobronchial cancers. When excited with blue-violet light, early neoplasia in the bronchi tend to show a decrease of autofluorescence in the green ...

2007

Design of an endoscopic optical reference to be used for autofluorescence bronchoscopy with a commercially available diagnostic autofluorescence endoscopy (DAFE) system

Georges Wagnières, Tanja Gabrecht, Blaise Lovisa, François André Borle

We present the design of a sterilizable optical reference to characterize and quantify the inter-patient variations in tissue autofluorescence during autofluorescence bronchoscopy with Richard Wolf's diagnostic autofluorescence endoscopy (DAFE) system. The ...

Institute of Physics2007

Blue-violet excited autofluorescence spectroscopy and imaging of normal and cancerous human bronchial tissue after formalin fixation

Georges Wagnières, Tanja Gabrecht

Autofluorescence (AF) imaging is a powerful tool for the detection of (pre-)neoplastic lesions in the bronchi. Several endoscopic imaging systems exploit the spectral and intensity contrast of AF between healthy and (pre-)neoplastic bronchial tissues, yet, ...

Wiley-Blackwell2007

Extracellular Matrix Remodeling by Dynamic Strain in a 3D Tissue Engineered Human Airway Wall Model

Melody Swartz

Airway wall remodeling is a hallmark of asthma, characterized by subepithelial thickening and extracellular matrix (ECM) remodeling. Mechanical stress due to hyperresponsive smooth muscle cells may contribute to this remodeling, but its extent and relevanc ...

2006

Clinical fluorescence spectroscopy and imaging for the detection of early carcinoma by autofluorescence bronchoscopy and the study of the protoporphyrin IX pharmacokinetics in the endometrium

Tanja Gabrecht

The aim of this thesis is to optimise and gain fundamental information on two applications of photomedicine using fluorescence imaging and spectrofluorometry: (1) the detection of early bronchial cancer by autofluorescence imaging and (2) the endometrial a ...

EPFL2006

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