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Purpose: Age-related macular degeneration (AMD) has been associated with a number of polymorphisms in genes in the complement pathway. We examined the potential genotype-phenotype correlation of complement factor B (CFB) (R32Q) polymorphisms in Caucasian p ...
Although a multitude of halogenated compounds are naturally produced, interest in biodegradation of these often toxic compounds has mainly been driven by anthropogenic contamination of soils and aquifers with huge amounts of chlorinated solvents (tetra- an ...
Whenever we meet a person for the first time, we tend to attribute personality traits to him/her. The process takes place in less than a second and it is spontaneous and unconscious. While not necessarily accurate (attributed traits do not necessarily corr ...
Functional consequences of mutations in predisposition genes for familial cancer syndromes remain often elusive, especially when the corresponding gene products play pleiotropic functions and interact with numerous partners. Understanding the consequences ...
Objective To genetically and phenotypically describe a new ADAM9 homozygous mutation in a consanguineous family from Egypt with autosomal recessive cone-rod dystrophy (arCRD), anterior polar and posterior subcapsular cataract. Design, setting and participa ...
The arms race between predators and prey has led to morphological and behavioral adaptations. Different antipredator strategies can coexist within a population if each strategy is the result of a trade-off with competing demands. Antipredator behavior can ...
Anatomical structures and mechanisms linking genes to neuropsychiatric disorders are not deciphered. Reciprocal copy number variants at the 16p11.2 BP4-BP5 locus offer a unique opportunity to study the intermediate phenotypes in carriers at high risk for a ...
Invasion success is favoured by the introduction of pre-adapted genotypes. In addition, novel pressures in the introduced range may lead to phenotypic changes related to fitness or competitive ability of introduced plants. Polyploidy appears to be over-rep ...
While it is well known that the success of alien plants in new environments greatly depends on their functional traits, to date only a few other studies have tested whether coexisting alien and native species show converging or diverging functional attribu ...
The gastrointestinal tract harbors a complex and diverse microbiota that has an important role in host metabolism. Microbial diversity is influenced by a combination of environmental and host genetic factors and is associated with several polygenic disease ...