Publications associées à Grossophobie

Proteomics reveals unique plasma signatures in constitutional thinness

Purpose Studying the plasma proteome of control versus constitutionally thin (CT) individuals, exposed to overfeeding, may give insights into weight-gain management, providing relevant information to the clinical entity of weight-gain resistant CT, and dis ...

WILEY-V C H VERLAG GMBH2022

The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial

Nicholas Edward Phillips, Alexandra Hemmer

Objective This study explored the impact of time-restricted eating (TRE) versus standard dietary advice (SDA) on bone health. Methods Adults with >= 1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours) or SDA (food p ...

WILEY2022

Short Article Hypothalamic bile acid-TGR5 signaling protects from obesity

Kristina Schoonjans, Alessia Perino

Bile acids (BAs) improve metabolism and exert anti-obesity effects through the activation of the Takeda G protein-coupled receptor 5 (TGR5) in peripheral tissues. TGR5 is also found in the brain hypothalamus, but whether hypothalamic BA signaling is implic ...

Cell Press2021

Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy

Jacques Fellay, Christian Hammer, Christian Axel Wandall Thorball, Monia Guidi, Thierry Buclin

Objective. There is limited data on abdominal obesity and the influence of genetics on weight change after ant iretroviral therapy (ART) initiation. We assessed body mass index (BMI) and waist hip ration (WHR) change over time in the Swiss HIV Cohort study ...

OXFORD UNIV PRESS INC2020

Enoxacin induces oxidative metabolism and mitigates obesity by regulating adipose tissue miRNA expression

Johan Auwerx, Tanes Imamura de Lima

MicroRNAs (miRNAs) have been implicated in oxidative metabolism and brown/beige adipocyte identity. Here, we tested whether widespread changes in miRNA expression promoted by treatment with the small-molecule enoxacin cause browning and prevent obesity. En ...

AMER ASSOC ADVANCEMENT SCIENCE2020

Multiaxial fatigue analysis of high-strength steel welded joints using generalized local approaches

Martin Antonio René Garcia

The objective of this thesis is to improve methods for predicting the fatigue life, multiaxial or not, of mild- and more particularly high-strength steels using local approaches that have the capacity to be applicable to almost any cases, hence the term ge ...

EPFL2020

Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism

Patrick Descombes, Hélène Ruffieux, Sylviane Métairon, Jörg Hager, Nele Gheldof

Hundreds of genetic variants have been associated with Body Mass Index (BMI) through genome-wide association studies (GWAS) using observational cohorts. However, the genetic contribution to efficient weight loss in response to dietary intervention remains ...

Springer2019

Overlapping spatial clusters of sugar-sweetened beverage intake and body mass index in Geneva state, Switzerland

Stéphane Joost, Idris Guessous, David Nicolas De Ridder, Beatrice Bacchilega

Background: Obesity and obesity-related diseases represent a major public health concern. Recently, studies have substantiated the role of sugar-sweetened beverages (SSBs) consumption in the development of these diseases.The fine identification of populati ...

Springer2019

Persistent spatial clusters of high body mass index in a Swiss urban population as revealed by the 5-year GeoCoLaus longitudinal study

Stéphane Joost, Solange Catherine Gaillard, Murielle Bochud, Idris Guessous, Joël Chételat, Fred Michel Paccaud

OBJECTIVE Body mass index (BMI) may cluster in space among adults and be spatially dependent. Whether and how BMI clusters evolve over time in a population is currently unknown. We aimed to determine the spatial dependence of BMI and its 5-year evolution i ...

Bmj Publishing Group2016

Anti-Obesity and Anti-Hyperglycemic Effects of Cinnamaldehyde via altered Ghrelin Secretion and Functional impact on Food Intake and Gastric Emptying

Henry Markram, Julie Meystre, Maurizio Ferdinando Pezzoli, Johannes Le Coutre, Susana Camacho Romero

Cinnamon extract is associated to different health benefits but the active ingredients or pathways are unknown. Cinnamaldehyde (CIN) imparts the characteristic flavor to cinnamon and is known to be the main agonist of transient receptor potential-ankyrin r ...

Nature Publishing Group2015