Concept
Myélite transverse
Publications associées (11)
Prediction of post-stroke motor recovery benefits from measures of sub-acute widespread network damages
Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Elvira Pirondini, Cyprien Alban Félicien Rivier
Rivier et al. report that global measures of brain connectivity estimated by introducing virtual lesions in healthy structural connectomes significantly increase the accuracy of motor recovery prediction in stroke patients when added to focal and clinical ...
OXFORD UNIV PRESS2023CVSnet: A machine learning approach for automated central vein sign assessment in multiple sclerosis
Meritxell Bach Cuadra, Tobias Kober, Reto Meuli, Cristina Granziera, Jonas Richiardi, João Pedro Forjaco Jorge, Mario Joao Fartaria de Oliveira, Francesco La Rosa
The central vein sign (CVS) is an efficient imaging biomarker for multiple sclerosis (MS) diagnosis, but its application in clinical routine is limited by inter-rater variability and the expenditure of time associated with manual assessment. We describe a ...
2020Soft multimodal neural interfaces for unravelling sensory neurological circuits
Frédéric Pierre Gérald Michoud
Diseases or injuries affecting the nervous system can dramatically disrupt the quality of life. Despite extensive efforts towards treating dysfunctional nervous systems, the pharmacological and electrical approaches generally involved lack the temporal and ...
EPFL2019Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension
Matthias Lütolf, Jeffrey Alan Hubbell, Delphine Lorraine Perle Blondel
An enzymatically cross-linked polyethylene glycol (PEG)-based hydrogel was engineered to promote and align nerve cells in a three-dimensional manner. To render the injectable, otherwise bioinert, PEG-based material supportive for cell growth, its mechanica ...
AMER CHEMICAL SOC2019Required growth facilitators propel axon regeneration across complete spinal cord injury
Grégoire Courtine, Mark Andrew Anderson, Nicholas David James, Cheng Wang, Sabry Leonardo Barlatey, Michael V. Sofroniew, Zhigang He
Transected axons fail to regrow across anatomically complete spinal cord injuries (SCI) in adults. Diverse molecules can partially facilitate or attenuate axon growth during development or after injury1,2,3, but efficient reversal of this regrowth failure ...
2018Influence of Zinc Anisotropy on Solidification Microstructures: Experimental Results and Phase-Field Simulations
Due to a distortion of its hexagonal unit cell along the c-axis compared to hexagonal-close-packed metals (c/a = 1.856 instead of 1.633), zinc is characterised by a large anisotropy of its solid-liquid interfacial energy. While previous studies have focuse ...
EPFL2015Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates
Grégoire Courtine, Quentin Barraud, Pavel Musienko, Rubia van den Brand, Lucia Florinda Friedli Wittler
Experimental and clinical studies suggest that primate species exhibit greater recovery after lateralized compared to symmetrical spinal cord injuries. Although this observation has major implications for designing clinical trials and translational therapi ...
American Association for the Advancement of Science2015A pipeline approach with spatial information for segmenting multiple sclerosis lesions on brain magnetic resonance imaging
Meritxell Bach Cuadra, Mariano Cabezas Grebol
Conventional magnetic resonance imaging (MRI) techniques are highly sensitive to detect multiple sclerosis (MS) plaques, enabling a quantitative assessment of inflammatory activity and lesion load. In quantitative analysis of focal lesions, manual or semi-a ...
2011Conditions for recovery of sparse signals correlated by local transforms
This paper addresses the problem of correct recovery of multiple sparse correlated signals using distributed thresholding. We consider the scenario where multiple sensors capture the same event, but observe different signals that are correlated by local tr ...
2009Combinatory electrical and pharmacological neuroprosthetic interfaces to regain motor function after spinal cord injury
Grégoire Courtine, Pavel Musienko, Rubia van den Brand
Severe lesions of the rodent or human spinal cord lead to permanent paralysis of the legs. Here, we review novel evidences suggesting that interventions combining pharmacological and electrical stimulations of the spinal cord have a high potential to promo ...
2009