Publications associées à Cobalamin biosynthesis

Proteome adaptations of the organohalide-respiring Desulfitobacterium hafniense strain DCB-2 to various energy metabolisms

Christof Holliger, Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Florence Armand

IntroductionDesulfitobacterium hafniense was isolated for its ability to use organohalogens as terminal electron acceptors via organohalide respiration (OHR). In contrast to obligate OHR bacteria, Desulfitobacterium spp. show a highly versatile energy meta ...

FRONTIERS MEDIA SA2023

Vitamin B12 deficiency and impaired expression of amnionless during aging

Sonia Karaz, Laurence Goulet, Alice Pannerec

Background Physical frailty and loss of mobility in elderly individuals lead to reduced independence, quality of life, and increased mortality. Vitamin B12 deficiency has been linked to several age-related chronic diseases, including in the musculo-skeleta ...

2018

Functional genomics of corrinoid starvation in the organohalide-respiring bacterium Dehalobacter restrictus strain PER-K23

Christof Holliger, Julien Maillard, Yue Lu, Aamani Rupakula Boyanapalli, Hauke Smidt

De novo comnoid biosynthesis represents one of the most complicated metabolic pathways in nature. Organohalide-respiring bacteria (OHRB) have developed different strategies to deal with their need of corrinoid, as it is an essential cofactor of reductive d ...

Frontiers Research Foundation2015

Proteome analysis of the response of Dehalobacter restrictus to cobalamin starvation

Christof Holliger, Julien Maillard, Aamani Rupakula Boyanapalli, Hauke Smidt

Dehalobacter restrictus strain PER-K23 is an obligate organohalide respiring microorganism known to solely use tetra- or trichloroethene as electron acceptors with H2 as electron donor. The catalytic enzyme, PceA, contains a corrinoid as cofactor, a trait ...

2014

Corrinoid Auxotrophy in the Obligate Organohalide-Respiring Dehalobacter restrictus strain PER-K23

Christof Holliger, Julien Maillard, Yue Lu, Aamani Rupakula Boyanapalli, Hauke Smidt

Introduction: Corrinoids are an essential cofactor of reductive dehalogenases, the key enzymes of organohalide respiration (OHR). Dehalobacter restrictus strain PER-K23 is an obligate OHR bacterium able to conserve energy with tetrachloroethene, but is una ...

2014

Corrinoid auxotrophy in the obligate organohalide-respiring Dehalobacter restrictus strain PER-K23

Christof Holliger, Julien Maillard, Yue Lu, Aamani Rupakula Boyanapalli, Hauke Smidt

Background Corrinoids are an essential cofactor of reductive dehalogenases, the key enzymes of organohalide respiration (OHR). Dehalobacter restrictus is an obligate OHR bacterium (OHRB) able to conserve energy with tetrachloroethene, but is unable to de n ...

2014

Salvage of the essential corrinoid cofactor in Dehalobacter restrictus

Christof Holliger, Julien Maillard, Yue Lu, Aamani Rupakula Boyanapalli, Sébastien Keller, Hauke Smidt

The corrinoid cofactor is essential for organohalide respiration (OHR), a bacterial metabolism assisting towards environmental depollution. Two different strategies for obtaining corrinoids, are used by OHR bacteria, either de novo biosynthesis or salvagin ...

2014

Regulation of the Corrinoid Metabolism in Desulfitobacteria

Christof Holliger, Julien Maillard, Emmanuelle Rohrbach, Aurélie Duret

The corrinoid cofactor is essential to organohalide respiration (OHR) as key element in virtually all reductive dehalogenases. Desulfitobacteria, and more particularly D. hafniense, represent a group of versatile OHR bacteria able to produce corrinoids de ...

2014

Functional characterization of a new tetrachloroethene reductive dehalogenase of Sulfurospirillum spp. identified in mixed cultures

Christof Holliger, Julien Maillard, Géraldine Florence Buttet

Recent analysis of a set of reductive dehalogenases revealed that sequence similarity and substrate specificity are not correlated, making functional prediction from sequences difficult (1). To this respect, several enrichment cultures were investigated fo ...

2014

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Cobalamin biosynthesis

Proteome adaptations of the organohalide-respiring Desulfitobacterium hafniense strain DCB-2 to various energy metabolisms

Vitamin B12 deficiency and impaired expression of amnionless during aging

Functional genomics of corrinoid starvation in the organohalide-respiring bacterium Dehalobacter restrictus strain PER-K23

Understanding the metabolism of tetrachloroethene-respiring Dehalobacter restrictus

Proteome analysis of the response of Dehalobacter restrictus to cobalamin starvation

Corrinoid Auxotrophy in the Obligate Organohalide-Respiring Dehalobacter restrictus strain PER-K23

Corrinoid auxotrophy in the obligate organohalide-respiring Dehalobacter restrictus strain PER-K23

Salvage of the essential corrinoid cofactor in Dehalobacter restrictus

Regulation of the Corrinoid Metabolism in Desulfitobacteria

Functional characterization of a new tetrachloroethene reductive dehalogenase of Sulfurospirillum spp. identified in mixed cultures

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Chattez avec Graph Search

Corrinoid auxotrophy in the obligate organohalide-respiring Dehalobacter restrictus strain PER-K23

Salvage of the essential corrinoid cofactor in Dehalobacter restrictus

Regulation of the Corrinoid Metabolism in Desulfitobacteria

Functional characterization of a new tetrachloroethene reductive dehalogenase of Sulfurospirillum spp. identified in mixed cultures

Proteome analysis of the response of Dehalobacter restrictus to cobalamin starvation

Understanding the metabolism of tetrachloroethene-respiring Dehalobacter restrictus

Functional genomics of corrinoid starvation in the organohalide-respiring bacterium Dehalobacter restrictus strain PER-K23

Vitamin B12 deficiency and impaired expression of amnionless during aging

Corrinoid Auxotrophy in the Obligate Organohalide-Respiring Dehalobacter restrictus strain PER-K23