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Publications associées (32)
Drug Screening in C. elegans to identify new pharmacological mitochondrial stress inducers
Mitochondria are essential organelles participating in numerous cellular functions, including energy harvesting, regulation of homeostasis and apoptosis. Changes in mitochondrial number, morphology, and function not only impact cellular metabolism but also ...
EPFL2024How Vibrio cholerae adapts to the environment: from cell shape transitions to antagonistic behavior
The bacterium Vibrio cholerae is the causative agent of the diarrheal disease cholera, which affects millions of people every year. Apart from being a human pathogen, V. cholerae is also a common member of aquatic habitats. Whilst the mechanism that allow ...
EPFL2022Ammonium is the preferred source of nitrogen for planktonic foraminifer and their dinoflagellate symbionts
Anders Meibom, Charlotte Madeleine Nicole Lekieffre, Emmanuelle Geslin
The symbiotic planktonic foraminiferaOrbulina universainhabits open ocean oligotrophic ecosystems where dissolved nutrients are scarce and often limit biological productivity. It has previously been proposed thatO. universameets its nitrogen (N) requiremen ...
ROYAL SOC2020Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip
Maartje Martina Cornelia Bastings
Extracellular vesicles (EVs) derived from various stem cell sources induce cardioprotective effects during ischemia-reperfusion injury (IRI). These have been attributed mainly to the antiapoptotic, proangiogenic, microRNA (miRNA) cargo within the stem cell ...
AMER ASSOC ADVANCEMENT SCIENCE2020Time-lapse high-resolution microscopy to study the morphogenesis of microorganisms
Mélanie Thérèse Marie Hannebelle
Mycobacterium tuberculosis, the etiological agent for the tuberculosis disease, is a bacterial pathogen thought to infect about a quarter of the global human population. It is the first cause of death among infectious diseases, and is most prevalent in low ...
EPFL2020Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation
Suliana Manley, Christian Sieben
Influenza A virus (IAV) binds its host cell using the major viral surface protein hemagglutinin (HA). HA recognizes sialic acid, a plasma membrane glycan that functions as the specific primary attachment factor (AF). Since sialic acid alone cannot fulfill ...
2020Bacterial cell cycle dynamics: size regulation during exponential growth and role of polyphosphate during starvation response
Bacteria are the most diverse and abundant kingdom of life and have adapted to survive and thrive in habitats around the globe. When provided with ample nutrients they grow and divide at staggering rates, increasing their population exponentially. Upon nut ...
EPFL2019Cellular ultrastructure in benthic foraminifera: general observations and focus on kleptoplasts.
Anders Meibom, Charlotte Madeleine Nicole Lekieffre, Emmanuelle Geslin
Research of the past few decades has revealed a great variability of metabolisms (e.g. adaptation to different microhabitats, feeding strategies, symbiosis, survival to stressful conditions) among benthic foraminiferal species. This metabolic variety is re ...
2018Dispositif et procédé pour l'évaluation de la contraction cellulaire
Boris Hinz, Pierre Jean Arnould Wipff
A method for assessing cell contraction includes adhering contractile cells to an oxidized and cellular adhesion activated surface of a biocompatible silicone elastomer film. The biocompatible silicone elastomer film allows the cells to contract and wrinkl ...
2017An Amidase_3 domain-containing N-acetylmuramyl-L-alanine amidase is required for mycobacterial cell division
Neeraj Dhar, Ashima Bhaskar, Dong Li
Mycobacteria possess a multi-layered cell wall that requires extensive remodelling during cell division. We investigated the role of an amidase_3 domain-containing N-acetylmuramyl-L-alanine amidase, a peptidoglycan remodelling enzyme implicated in cell div ...
Nature Publishing Group2017