Concept
Gene polymorphism
Publications associées (99)
A single nucleotide polymorphism determines constitutive versus inducible type VI secretion in Vibrio cholerae
Melanie Blokesch, Sandrine Stutzmann, Alexis Joseph Proutière, Loriane Bader, Milena Jadwiga Jaskolska
Vibrio cholerae is a well-studied human pathogen that is also a common inhabitant of marine habitats. In both environments, the bacterium is subject to interbacterial competition. A molecular nanomachine that is often involved in such competitive behavior ...
2022Single nucleotide polymorphism determines constitutive versus inducible type VI secretion in Vibrio cholerae
Melanie Blokesch, Sandrine Stutzmann, Alexis Joseph Proutière, Loriane Bader, Natalia Carolina Drebes Dorr, Milena Jadwiga Jaskolska
Vibrio cholerae is a well-studied human pathogen that is also a common inhabitant of marine habitats. In both environments, the bacterium is subject to interbacterial competition. A molecular nanomachine that is often involved in such competitive behavior ...
2022A Baseline Cellular Antiviral State Is Maintained by cGAS and Its Most Frequent Naturally Occurring Variant rs610913
Jacques Fellay, Christian Axel Wandall Thorball, Shuting Xu
Upon recognition of aberrantly located DNA, the innate immune sensor cyclic GMP-AMP synthase (cGAS) activates stimulator of IFN genes (STING)/IFN regulatory factor (IRF)3-driven antiviral responses. In this study, we characterized the ability of a specific ...
AMER ASSOC IMMUNOLOGISTS2022Essential role of Cp190 in physical and regulatory boundary formation
Nicolas Jean Philippe Guex, Julien Dorier, Christian Iseli
Boundaries in animal genomes delimit contact domains with enhanced internal contact frequencies and have debated functions in limiting regulatory cross-talk between domains and guiding enhancers to target promoters. Most mammalian boundaries form by stalli ...
2022