Concept

Muscle weakness

Publications associées (46)

Protocol for the PreventIT feasibility randomised controlled trial of a lifestyle-integrated exercise intervention in young older adults

Introduction The European population is rapidly ageing. In order to handle substantial future challenges in the healthcare system, we need to shift focus from treatment towards health promotion. The PreventIT project has adapted the Lifestyle-integrated Ex ...

BMJ2019

Wearable System for Spinal Cord Injury Rehabilitation with Muscle Fatigue Feedback

Sandro Carrara, Francesca Stradolini, Danilo Demarchi, Diego Marino, Sofia Milanese

The design, realization and verification of a system for personalized rehabilitation of Spinal Cord Injury (SCI) patients are here presented. It consists of two main parts: (i) one induces in the patient the physiotherapic movement proposed by the trainer ...

IEEE2018

Wearable System for Spinal Cord Injury Rehabilitation with Muscle Fatigue Feedback

Sandro Carrara, Francesca Stradolini, Danilo Demarchi, Diego Marino, Sofia Milanese

IEEE2018

Hybrid peripheral-spinal neuroprosthesis for refined motor execution after paralysis

Sophie Marie Marthe Wurth

Spinal cord injury (SCI) disrupts the communication between the brain and the spinal circuits responsible for movement, thereby causing severe motor deficits. Current strategies to restore function to paralyzed limbs have separately investigated electrical ...

EPFL2018

Pathogenic commonalities between spinal muscular atrophy and amyotrophic lateral sclerosis: Converging roads to therapeutic development

Bernard Schneider

Spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS) are the two most common motoneuron disorders, which share typical pathological hallmarks while remaining genetically distinct. Indeed, SMA is caused by deletions or mutations in the surv ...

ELSEVIER SCIENCE BV2018

Neuromodulation in the restoration of function after spinal cord injury

Nicholas David James

Neuromodulation, the use of electrical interfaces to alter neuronal activity, has been successful as a treatment approach in several neurological disorders, including deep brain stimulation for Parkinson's disease and epidural spinal stimulation for chroni ...

2018

Muscle Activation Variability Is Inversely Correlated with Walking Speed

Auke Ijspeert, Florin Dzeladini, Amy Roning Wu, Cole Stewart Simpson, Amandine Grappe

Individuals withmotor impairments typically walk at much slower speeds than their unimpaired counterparts, yet their gait data is still evaluated against the relatively faster gait of healthy subjects. Therefore a good understanding of unimpaired gait at e ...

Springer International Publishing Ag2017

The Myosuit: Bi-articular Anti-gravity Exosuit That Reduces Hip Extensor Activity in Sitting Transfers

Muscle weakness—which can result from neurological injuries, genetic disorders, or typical aging—can affect a person's mobility and quality of life. For many people with muscle weakness, assistive devices provide the means to regain mobility and independen ...

2017

PPAR delta Promotes Running Endurance by Preserving Glucose

Johan Auwerx, Hao Li, Vincenzo Sorrentino

Management of energy stores is critical during endurance exercise; a shift in substrate utilization from glucose toward fat is a hallmark of trained muscle. Here we show that this key metabolic adaptation is both dependent on muscle PPAR delta and stimulat ...

Cell Press2017

Muscle activation variability is inversely correlated with walking speed

Auke Ijspeert, Florin Dzeladini, Cole Stewart Simpson, Amandine Grappe

Individuals with motor impairments typically walk at much slower speeds than their unimpaired counter- parts, yet their gait data is still evaluated against the relatively faster gait of healthy subjects. Therefore a good understanding of unimpaired gait a ...

Springer2016

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