Concept

Neuronal migration disorder

Publications associées (33)

A post-processing pipeline to reconstruct the developing fetal brain using low-resolution MRI

Jean-Philippe Thiran, Meritxell Bach Cuadra, Marie Schaer

Introduction. Development of the fetal brain surface with concomitant gyrification is one of the major maturational processes of the human brain. First delineated by postmortem studies or by ultrasound, MRI has recently become a powerful tool for studying ...

2010

Emergent Dynamics in Neocortical Microcircuits

Rodrigo de Campos Perin

Interactions among neurons can take place in a wide variety of forms. It is the goal of this thesis to investigate the properties and implications of a number of these interactions that we believe are relevant for information processing in the brain. Neuro ...

EPFL2010

Integration of a virtual reality based arm in primary somatosensory cortex

Hannes Bleuler, Solaiman Shokur, Miguel Nicolelis, Mikhail Lebedev

Abstract: Recent advances in brain-machine interfaces (BMIs) have demonstrated the possibility of motor neuroprosthetics directly controlled by brain activity. Ideally neuroprosthetic limbs should be integrated in the body schema of the subject. To explore ...

2010

Interpretation of neuronal response properties with simplified neuron models

Laurent Badel

Computational neuroscience is a branch of the neurosciences that attempts to elucidate the principles underlying the operation of neurons with the help of mathematical modeling. In contrast with a number of fields pursuing a tightly related goal, such as m ...

EPFL2009

Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex

Freddy Radtke

Neuronal migration is a fundamental component of brain development whose failure is associated with various neurological and psychiatric disorders. Reelin is essential for the stereotypical inside-out sequential lamination of the neocortex, but the molecul ...

2008

Transcranial direct current stimulation: State of the art 2008

Friedhelm Christoph Hummel

Effects of weak electrical currents on brain and neuronal function were first described decades ago. Recently, DC polarization of the brain was reintroduced as a noninvasive technique to alter cortical activity in humans. Beyond this, transcranial direct c ...

2008

Comprehensive spatiotemporal transcriptomic analyses of the ganglionic eminences demonstrate the uniqueness of its caudal subdivision

Mauro Delorenzi, Didier Surdez, Susan Willi Monnerat

The elucidation of mechanisms underlying telencephalic neural development has been limited by the lack of knowledge regarding the molecular and cellular aspects of the ganglionic eminence (GE), an embryonic structure that supplies the brain with diverse se ...

Elsevier2008

Abnormal patterns of cortical gyrification in velo-cardio-facial syndrome (deletion 22q11.2): an MRI study

Marie Schaer, François Lazeyras

Velo-cardio-facial syndrome (VCFS), also known as 22q11.2 deletion syndrome, is a common genetic condition associated with increased risk for developing schizophrenia. Given that cortical malformations play an integral role in the pattern of neuroanatomica ...

2006

A New Method For Measuring Cortical Folding In A 3D Space From MR Images

Jean-Philippe Thiran, Meritxell Bach Cuadra

Development of technologies in the field of neuroimaging brought an increase interest in the quantification of cortical folding (gyrification), notably for neurogenetic and psychiatric disorders that may result from an early abnormal cortical development. ...

2006

Segmentation of diffusion weighted MRI using the level set framework

Lisa Jonasson

Medical imaging is a rapidly growing field in which diffusion imaging is a recently developed modality. This novel imaging contrast permits in-vivo measurement of the diffusion of water molecules. This is particularly interesting in brain imaging where the ...

EPFL2005

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