Concept

Bladder stone

Publications associées (39)

Detection of early bladder carcinoma by fluorescence cystoscopy with Hexvix: optical characterization of a high magnification cystoscope

Hubert van den Bergh, Georges Wagnières, Blaise Lovisa

Fluorescence detection of early superficial bladder cancer has been well established over the last years. This technique exploits the selective production and accumulation within cancerous tissues of photoactive porphyrins (PaP), mainly protoporphyrin IX ( ...

SPIE2009

Tissue engineering of the bladder

Catharina Adelöw

Stem cell use in bladder tissue engineering is a recently addressed area of investigation that has generated excitement as a novel way to restore and regenerate lost or damaged urinary bladder tissue. The remodelling of smooth muscle plays a significant ro ...

EPFL2009

Bladder cancer detection by fluorescence imaging with Hexvix®: Analysis and processing of images obtained during high magnification cystoscopy

Hubert van den Bergh, Georges Wagnières, Blaise Lovisa

Fluorescence cystoscopy has been recently acknowledged as a useful method to detect early superficial bladder cancer, even flat lesions. After the instillation of hexaminolevulinic acid (Hexvix®) in the bladder for about an hour, photoactivable porphyrins ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2009

Bladder cancer detection by fluorescence imaging with Hexvix®: Analysis and processing of images obtained during high magnification cystoscopy

Hubert van den Bergh, Georges Wagnières, Blaise Lovisa

2009

Photodynamic diagnostics in the urinary tract. Consensus paper of the Working Group for Oncology of the German Society for Urology

Hubert van den Bergh

Because of the frequency of occurrence and the long protracted course, bladder carcinoma is the most expensive solid tumor in terms of costs, from diagnosis to death of the patient. The most important cost factor within the total cost is the treatment of r ...

Springer Verlag2008

Hexyl-aminolevulinate-mediated photodynamic therapy: how to spare normal urothelium. An in vitro approach

Hubert van den Bergh, Pavel Kucera, Céline Ritter Schenk

Photodynamic therapy (PDT) of superficial bladder cancer may cause damages to the normal surrounding bladder wall. Prevention of these is important for bladder healing. We studied the influence of photosensitizer concentration, irradiation parameters, and ...

Wiley-Blackwell2007

Comparison of aminolevulinic acid and hexylester aminolevulinate induced protoporphyrin IX distribution in human bladder cancer

Pavel Kucera

Successful photodynamic therapy of epithelial cancer requires a specific photosensitization of malignant tissue. We evaluate the intensity and localization of protoporphyrin IX (PpIX) in superficial transitional cell carcinoma and nonmalignant cells of the ...

Elsevier2003

On the influence of the instillation time on the results of HAL (Hexvix®) fluorescence detection of superficial bladder cancer

Hubert van den Bergh, Georges Wagnières

Hexyl aminolevulinate (HAL) fluorescence cystoscopy is being investigated as a new diagnostic tool for the detection of flat urothelial malignancies in bladder cancers. However, the influence of the bladder instillation time on the performance of this dete ...

2003

Biotechnology. A new-for-old urinary bladder

Jeffrey Alan Hubbell

[on SciFinder (R)] ...

1999

Photodetection of early human bladder cancer based on the fluorescence of 5-aminolaevulinic acid hexylester-induced protoporphyrin IX: a pilot study

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Pavel Kucera

Exogenous administration of 5-aminolaevulinic acid (ALA) is becoming widely used to enhance the endogenous synthesis of protoporphyrin IX (PpIX) in photodynamic therapy (PDT) and fluorescence photodetection (PD). Recently, results have shown that the chemi ...

1999

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