Concept

Colonne vertébrale

Publications associées (81)

Analysis of the stability of a posterior fusion system for the treatment of burst fractures

Dominique Pioletti, Arne Christian Vogel, Martin Aeberhard

In the framework of spine traumatology, burst fractures are severe and are often caused by car accidents or by falls. The vertebra breaks under the traumatic compression and pieces of it are shattered in all directions. This type of fracture is often treat ...

2007

Biomechanical investigation of a new implant for cervical spine fusion

Dominique Pioletti, Arne Christian Vogel, Michael Davatz

The project consists of: - mechanical tests of the prototype of the new implant and comparison to existing anterior fixation systems in a bone model material; - a literature review in order to classify the test results; - the development of a finite elemen ...

2007

Completing the set of h/E(spl) cyclic genes in zebrafish: her12 and her15 reveal novel modes of expression and contribute to the segmentation clock

Andrew Charles Oates

Somitogenesis is the key developmental process that lays down the framework for a metameric body in vertebrates. Somites are generated from the un-segmented presomitic mesoderm (PSM) by a pre-patterning process driven by a molecular oscillator termed the s ...

2007

From swimming to walking with a salamander robot driven by a spinal cord model

Auke Ijspeert, Alessandro Crespi

The transition from aquatic to terrestrial locomotion was a key development in vertebrate evolution. We present a spinal cord model and its implementation in an amphibious salamander robot that demonstrates how a primitive neural circuit for swimming can b ...

2007

Plasticity of Spinal Cord Reflexes After a Complete Transection in Adult Rats: Relationship to Stepping Ability

Grégoire Courtine

Changes in epidurally induced (S1) spinal cord reflexes were studied as a function of the level of restoration of stepping ability after spinal cord transection (ST). Three types of responses were observed. The early response (ER) had a latency of 2.5 to 3 ...

2006

A t(2;8) balanced translocation with breakpoints near the human HOXD complex causes mesomelic dysplasia and vertebral defects

Denis Duboule

Mesomelic dysplasia is a severe shortening of forearms and forelegs, and is found in several distinct human syndromes. Here, we report the cloning of the breakpoints of a human t(2;8)(q31;p21) balanced translocation associated with mesomelic dysplasia of t ...

2002

Accurate physical mobility analysis of patients treated by neuromodulation

Kamiar Aminian, Philippe Robert, Anisoara Ionescu, Bijan Najafi

Spinal cord stimulation (i.e. the electrical stimulation of the dorsal columns of the spinal cord) isincreasingly used for the treatment of intractable pain syndromes due to vascular or neurogenicdisorders. Despite well-established safety and efficacy in p ...

2001

Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning

Denis Duboule, Jozsef Zakany

Hoxa-11 and Hoxd-11 are paralogous genes required for proper development of the vertebral column, the limbs, and the urogenital system. To further explore the functional relationship between these genes, as well as the potential rescue of one function by t ...

1996

Teleost HoxD and HoxA genes: comparison with tetrapods and functional evolution of the HOXD complex

Denis Duboule

In tetrapods, Hox genes are essential for the proper organization and development of axial structures. Experiments involving Hox gene inactivations have revealed their particularly important functions in the establishment of morphological transitions withi ...

1996

Differential expression of two different homeobox gene families during mouse tegument morphogenesis

Denis Duboule

The expression of six genes belonging to two different homeobox gene families was studied during the embryonic and postnatal morphogenesis of head and body regions of the mouse integument. The first family included the Otx1 and Otx2 genes, both related to ...

1994

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