Concept

Plaie

Publications associées (55)

Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice

Denis Duboule, Jozsef Zakany, Walter Wahli

We show here that the alpha, beta, and gamma isotypes of peroxisome proliferator-activated receptor (PPAR) are expressed in the mouse epidermis during fetal development and that they disappear progressively from the interfollicular epithelium after birth. ...

2001

Enzymatic incorporation of bioactive peptides into fibrin matrices enhances neurite extension

Patrick Aebischer, Jeffrey Alan Hubbell

Fibrin plays an important role in wound healing and regeneration, and enjoys widespread use in surgery and tissue engineering. The enzymatic activity of Factor XIIIa was employed to covalently incorporate exogenous bioactive peptides within fibrin during c ...

2000

PEG-based hydrogels for blocking, presenting and receiving information in the control of wound healing

Jeffrey Alan Hubbell

A review with 6 refs. of the use of adherent polymer hydrogels to prevent attachment of platelets to artery walls. Adhesion peptides incorporated in these hydrogels may further inhibit thrombogenesis and addnl. promote reendothelialization. Hydrogels with ...

1997

Optimization of photopolymerized bioerodible hydrogel properties for adhesion prevention

Jeffrey Alan Hubbell

The aim of this study was to optimize the properties of a lubricious bioerodible hydrogel barrier for the prevention of postoperative adhesions. Water-soluble macromers based on block copolymers of poly(ethylene glycol) (PEG) and poly(lactic acid) or poly( ...

1994

Local modulation of intracellular calcium levels near a single-cell wound in human endothelial monolayers

Jeffrey Alan Hubbell

An endothelial cell monolayer with a single mechanically lysed cell was used as a model to examine the extent, kinetics, and nature of local calcium mobilization in the neighborhood of a wound. Individual endothelial cells from confluent monolayers were me ...

1991

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