Publications associées (9)

Computational identification and experimental characterization of preferred downstream positions in human core promoters

Philipp Bucher, René Dreos

Author summary Transcription of genes by the RNA polymerase II enzyme initiates at a genomic region termed the core promoter. The core promoter is a regulatory region that may contain diverse short DNA sequence motifs/elements that confer specific properti ...
PUBLIC LIBRARY SCIENCE2021

Prediction of Regulatory Modules Comprising MicroRNAs and Target Genes

Giovanni De Micheli

Motivation: MicroRNAs are small endogenous RNAs that can play important regulatory roles via the RNA-interference pathway by targeting mRNAs for cleavage or translational repression. We propose a computational method to predict miRNA regulatory modules or ...
2005

Prediction of regulatory modules comprising microRNAs and target genes

Giovanni De Micheli

Motivation: MicroRNAs (miRNAs) are small endogenous RNAs that can play important regulatory roles via the RNA-interference pathway by targeting mRNAs for cleavage or translational repression. We propose a computational method to predict mi ...
Oxford University Press2005

Prediction and Analysis of Human MicroRNA Regulatory Modules

Giovanni De Micheli

MicroRNAs are a family of small, non-coding RNAs that regulate gene expression in a sequence-specific manner. We propose a computational method to predict miRNA regulatory modules or groups of miRNAs and target genes that are believed to participate cooper ...
2005

CleanEx: a database of heterogeneous gene expression data based on a consistent gene nomenclature

Philipp Bucher

The main goal of CleanEx is to provide access to public gene expression data via unique gene names. A second objective is to represent heterogeneous expression data produced by different technologies in a way that facilitates joint analysis and cross-data ...
2004

OOC-3, a novel putative transmembrane protein required for establishment of cortical domains and spindle orientation in the P(1) blastomere of C. elegans embryos

Pierre Gönczy

Asymmetric cell divisions require the establishment of an axis of polarity, which is subsequently communicated to downstream events. During the asymmetric cell division of the P(1) blastomere in C. elegans, establishment of polarity depends on the establis ...
2000

Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

Pierre Gönczy

Genome sequencing projects generate a wealth of information; however, the ultimate goal of such projects is to accelerate the identification of the biological function of genes. This creates a need for comprehensive studies to fill the gap between sequence ...
2000

Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2

Denis Duboule

We have isolated a murine homeobox-containing gene, Hox-5.1, by virtue of its relatedness to the Hox-1.4 gene. In situ hybridization to metaphase spreads mapped Hox-5.1 to band D of mouse chromosome 2. Sequence comparisons indicate that Hox-5.1 is the muri ...
1988

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