Publications associées à Gène rapporteur

Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae

Sebastian Maerkl, Shiyu Cheng, Hon Ming Andrew Yip, Evan James Olson, Michael Andrew Crone

Cells cope with and adapt to ever-changing environmental conditions. Sophisticated regulatory networks allow cells to adjust to these fluctuating environments. One such archetypal system is the Saccharomyces cerevisiae Pho regulon. When external inorganic ...

Washington2023

Generation of a Gal4-dependent gene recombination and illuminating mouse

Freddy Radtke

Cell labeling technologies, including the Cre/loxP system, are powerful tools in developmental biology. Although the conventional Cre/loxP system has been extensively used to label the expression of specific genes, it is less frequently used for labeling p ...

INT PRESS EDITING CENTRE INC2022

Development of Covalent Chitosan-Polyethylenimine Derivatives as Gene Delivery Vehicle: Synthesis, Characterization, and Evaluation

Sandrine Gerber, Céline Marie Anne Journot, Laura Camille Louise Nicolle

There is an increasing interest in cationic polymers as important constituents of non-viral gene delivery vectors. In the present study, we developed a versatile synthetic route for the production of covalent polymeric conjugates consisting of water-solubl ...

2021

Genetically encoded betaxanthin-based small-molecular fluorescent reporter for mammalian cells

Leo Scheller, Karl Gademann, Simon Sieber

We designed and engineered a dye production cassette encoding a heterologous pathway, including human tyrosine hydroxylase and Amanita muscaria 4,5-DOPA dioxygenase, for the biosynthesis of the betaxanthin family of plant and fungal pigments in mammalian c ...

2020

Hybrid Transcriptional Regulators for the Screening of Target DNA Motifs in Organohalide-Respiring Bacteria

Christof Holliger, Julien Maillard, Mathilde Stéphanie Willemin, Marie Vingerhoets

The bioremediation of persistent organohalide molecules under anoxic conditions mostly relies on the bacterial process called organohalide respiration (OHR). Organohalide-respiring bacteria (OHRB) are phylogenetically diverse anaerobic bacteria that share ...

2020

Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells

Florian Maria Wurm, Bernard Schneider, Vivianne Padrun, Daniel Roman Blessing, Gabriel Vachey, Nicole Déglon

Adeno-associated virus (AAV) vectors are currently among the most commonly applied for in vivo gene therapy approaches. The evaluation of vectors during clinical development requires the production of considerable amounts of highly pure and potent vectors. ...

2019

Luciferases with tunable emission wavelengths

Kai Johnsson, Luc Reymond, Rudolf Griss, Alberto Schena, Qiuliyang Yu, Olivier Vincent Sallin, Lin Xue, Julien Hiblot, Nicholas Clarke Hill, Marina Daniela Beatrice Sabbadini

We introduce luciferases whose emission maxima can be tuned to different wavelengths by chemical labeling. These tunable luciferases are generated by inserting the small luciferase NanoLuc into the structures of the self-labeling proteins SNAP-tag or HaloT ...

Wiley-Blackwell2017

Pancreatic α- and β-Cellular Clocks Have Distinct Molecular Properties and Impact on Islet Hormone Secretion and Gene Expression

Michaël Unser, Daniel Sage, Cédric Gobet, Frédéric Bruno Martin Gachon

A critical role of circadian oscillators in orchestrating insulin secretion and islet gene transcription has been demonstrated recently. However, these studies focused on whole islets and did not explore the interplay between α-cell and β-cell clocks. We p ...

2017

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Gène rapporteur

Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae

Generation of a Gal4-dependent gene recombination and illuminating mouse

Development of Covalent Chitosan-Polyethylenimine Derivatives as Gene Delivery Vehicle: Synthesis, Characterization, and Evaluation

Genetically encoded betaxanthin-based small-molecular fluorescent reporter for mammalian cells

Hybrid Transcriptional Regulators for the Screening of Target DNA Motifs in Organohalide-Respiring Bacteria

Mixture effects of drinking water disinfection by-products: implications for risk assessment

Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells

Design and validation of bioorthogonal probes for cellular disease models

Luciferases with tunable emission wavelengths

Pancreatic α- and β-Cellular Clocks Have Distinct Molecular Properties and Impact on Islet Hormone Secretion and Gene Expression

Graph Chatbot

Chattez avec Graph Search

Hybrid Transcriptional Regulators for the Screening of Target DNA Motifs in Organohalide-Respiring Bacteria

Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae

Generation of a Gal4-dependent gene recombination and illuminating mouse

Genetically encoded betaxanthin-based small-molecular fluorescent reporter for mammalian cells

Design and validation of bioorthogonal probes for cellular disease models

Luciferases with tunable emission wavelengths

Pancreatic α- and β-Cellular Clocks Have Distinct Molecular Properties and Impact on Islet Hormone Secretion and Gene Expression

Development of Covalent Chitosan-Polyethylenimine Derivatives as Gene Delivery Vehicle: Synthesis, Characterization, and Evaluation

Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells

Mixture effects of drinking water disinfection by-products: implications for risk assessment