Concept

Bromure d'éthidium

Publications associées (28)

A versatile method for quantification of DNA and PCR products based on time-resolved EuIII luminescence

Jean-Claude Bünzli, Anne-Sophie Chauvin, Caroline Vandevyver, Bo Song

A versatile and robust method for the determination of DNA and PCR products (

2008

Size-dependent free solution DNA electrophoresis in structured microfluidic systems

Jürgen Brugger

A new concept based on microstructuring techniques is presented to achieve size-dependent electrophoretic migration of DNA in free solution. Topographically structured microfluidic channels with periodical cavities in the range of the radius of gyration of ...

2003

Solution versus vapor growth of dipolar layers on activated oxide substrates

Frank Nüesch, Libero Zuppiroli, Michel Carrara

Monolayer adsorption of benzoic acid derivatives on activated oxide surfaces from solution and from the vapor phase are investigated with the view of modifying the work function of a conductive substrate. Para-substituted benzoic acids with a wide range of ...

American Chemical Society2003

Synthesis and applications of chemical probes for human O6-alkylguanine-DNA alkyltransferase

Kai Johnsson, Antje Keppler

The design and synthesis of chem. probes to study and to elucidate complex biol. problems is becoming an increasingly important field in chem. We are interested in the repair of O6-alkylated guanines in DNA, a DNA lesion that results from alkylation by S-a ...

2001

Dichloromethane mediated in vivo selection and functional characterization of rat glutathione S-transferase theta 1-1 variants

Julien Maillard, Séverine Vuilleumier Varisco

Methylobacterium dichloromethanicum DM4 is able to grow with dichloromethane as the sole carbon and energy source by using a dichloromethane dehalogenase/glutathione S-transferase (GST) for the conversion of dichloromethane to formaldehyde. Mammalian homol ...

2001

Long circulating half-life and high tumor selectivity of the photosensitizer meta-tetrahydroxyphenylchlorin conjugated to polyethylene glycol in nude mice grafted with a human colon carcinoma

Hubert van den Bergh, Georges Wagnières

In a model of nude mice bearing a human colon carcinoma xenograft, the biodistribution and tumor localization of metatetrahydroxyphenylchlorin (m-THPC) coupled to polyethylene glycol (PEG) were compared with those of the free form of this photosensitizer u ...

1998

Synthesis of (-)-6-(3'-Aminopropyloxy)Methyl-4-Demethoxy-6,7-Dideoxy-Daunomycinon, a New DNA Intercalator Related to Anthracyclines

Pierre Vogel

The hydrochloride of (-)-(8R)-8-acetyl-7,8,9,10-tetrahydro-6, 8-dihydroxy-11-[3'-aminopropyloxy)methyl]naphthacene-5, 12-dione was derived from 1-(dimethaxymethyl)-2,3,5,6-tetramethylidene-7-oxabicyclo[2.2.2] heptane and shown to be a moderate intercalator ...

1995

Hydrogel-based three-dimensional matrix for neural cells

Patrick Aebischer, Nicolas Bouche

The ability to organize cells in three dimensions (3D) is an important component of tissue engineering. This study sought to develop an extracellular matrix (ECM) equivalent with a physicochemical structure capable of supporting neurite extension from prim ...

1995

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