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Publications associées (95)
Urtica dioica Leaf Infusion Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Cisplatin Treatment
Urtica dioica (UD) has been widely used in traditional medicine due to its therapeutic benefits, including its anticancer effects. Natural compounds have a promising potential when used in combination with chemotherapeutic drugs. The present study explores ...
MDPI2023Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies
Henning Paul-Julius Stahlberg, Dongchun Ni
ABCG2 is an ATP-binding cassette transporter that exports a wide range of xenobiotic compounds and has been recognized as a contributing factor for multidrug resistance in cancer cells. Substrate and inhibitor interactions with ABCG2 have been extensively ...
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD2023Discovery and Development of Hyperthermia-Enhanced Treatments for Malignant Skin and Uveal Melanomas
Melanomas are among the deadliest cancers, with a high predisposition to metastasis and a bad prognosis in their late stages. The effectiveness of current therapeutic regimens remains suboptimal, and despite initial successes, treatment resistance emerges ...
EPFL2023Photoresponsive Nanocarriers Based on Lithium Niobate Nanoparticles for Harmonic Imaging and On-Demand Release of Anticancer Chemotherapeutics
Sandrine Gerber, Jérémy Vuilleumier, Adrian Stefan Gheata, Dario Diviani, Luigi Bonacina, Simon Kaiser
Nanoparticle-based drug delivery systems have the potential for increasing the efficiency of chemotherapeutics by enhancing the drug accumulation at specific target sites, therebyreducing adverse side effects and mitigating patient acquired resistance. In ...
2022