Concept

Potentialisation à long terme

Publications associées (355)

Pro-neurogenesis therapy rescues hippocampal-mediated learning and memory deficits in the ts65dn mouse model of Down syndrome

Down syndrome (DS) is the most frequent cause of mental retardation in adults and children. It has been proposed that cognitive disabilities associated with DS may be ascribed to neurogenesis impairment during both development and adulthood. This view is s ...

2010

Spike-timing dependent plasticity

Wulfram Gerstner

Spike Timing Dependent Plasticity (STDP) is a temporally asymmetric form of Hebbian learning induced by tight temporal correlations between the spikes of pre- and postsynaptic neurons. As with other forms of synaptic plasticity, it is widely believed that ...

2010

Long-Term Depression at Parallel Fiber to Golgi Cell Synapses

Michele Giugliano

Robberechts Q, Wijnants M, Giugliano M, De Schutter E. Longterm depression at parallel fiber to Golgi cell synapses. J Neurophysiol 104: 3413-3423, 2010. First published September 22, 2010; doi:10.1152/jn.00030.2010. Golgi cells (GoCs) are the primary inhi ...

2010

Controlled release nanoparticle-embedded coatings reduce the tissue reaction to neuroprostheses

Philippe Renaud, André Mercanzini, Philippe Colin, Jeffrey Alan Hubbell, Jean-Charles Bensadoun, Sai Reddy

Controlled release coatings were developed for neuroprostheses with the aim of combating the tissue reaction following implantation in the brain. The coatings consist of poly(propylene sulfide) drug-eluting nanoparticles embedded in a poly(ethylene oxide) ...

Elsevier2010

On The Road To A Neuroprosthetic Hand: A Novel Hand Grasp Orthosis Based on Functional Electrical Stimulation

José del Rocio Millán Ruiz, Robert Leeb, Michele Tavella, Miguel Joaquin Gubler

To patients who have lost the functionality of their hands as a result of a severe spinal cord injury or brain stroke, the development of new techniques for grasping is indispensable for reintegration and independency in daily life. Functional Electrical S ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2010

Emergent Connectivity Principles in the Neocortex

Imad Riachi

The neocortex makes up over 80% of the mammalian brain and is responsible for higher cognitive functions, processing of sensory inputs and orchestration of complex motor outputs. It is a 6-layered structure composed of billions of morphologically and elect ...

EPFL2010

Stress at learning facilitates memory formation by regulating AMPA receptor trafficking through a glucocorticoid action

Maria del Carmen Sandi Perez, Lisa Conboy

Stress and glucocorticoids (GCs) can facilitate memory formation. However, the molecular mechanisms mediating their effects are largely unknown. alpha-Amino-3-hydroxy-5- methyl-4-isoxazolepropionic acid (AMPA) receptor (AMPAR) trafficking has been implicat ...

Nature Publishing Group2010

Fatigue Life Prediction of Composites and Composite Structures, 1st Edition

The use of composites is growing in structural applications in many industries including aerospace, marine, wind turbine and civil engineering. There are uncertainties about the long term performance of these composites and how they will perform under cycl ...

Woodhead Publishing2010

Decoding of attention deployment

Michael Herzog, Gijs Plomp, Yvonne Evelina Thunell

Attending to an object can strongly modulate the neural processing of this object. Using average EEG, it was shown that small differences in the focus of attention yield large and long lasting changes in brain dynamics (Plomp et al, 2009). Here, we show th ...

2010

Rat model: neural substrates of the battered woman syndrome

Xavier Fontana

This study is part of a long term study on a male rat model of peripubertal stress in the Laboratory of Behavioural Genetics that shows increase aggressive behaviours against their partners. We are using here these rats in order to create a female rat mode ...

2010

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