Publications associées (26)

In vitro-transfusional model for red-blood-cell study: the advantage of lowering hematocrit

Gerardo Turcatti, David Crettaz, Michel Prudent, Manon Sandra Bardyn

Background - Thequalityof red blood cells (RBCs) stored in red cell concentrates (RCCs) is influenced by processing, storage and donor characteristics, and can have a clinical impact on transfused patients. To evaluate RBC properties and their potential im ...
Simtipro Srl2023

The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study

Constantin Tuleasca, Krisztian Homicsko, Filipe Amândio Brandão Sanches Vong Martins, Olivier Michielin, Alexandre Wicky

Background Evidence pointing to a synergistic effect of stereotactic radiosurgery (SRS) with concurrent immunotherapy or targeted therapy in patients with melanoma brain metastases (BM) is increasing. We aimed to analyze the effect on overall survival (OS) ...
SPRINGER2020

Inflammation clues in STING protein structure

Andrea Ablasser

The STING protein aids intracellular defences by triggering inflammation. Studies that uncover how STING is activated might lead to strategies for targeting this protein in the treatment of cancer or autoimmune diseases. ...
NATURE PUBLISHING GROUP2019

De novo identification of lipid II binding lipopeptides with antibacterial activity against vancomycin-resistant bacteria

Inmaculada Rentero Rebollo

Creative strategies for identifying new antibiotics are essential to addressing the looming threat of a post-antibiotic era. We here report the use of a targeted peptide phage display screen as a means of generating novel antimicrobial lipopeptides. Specif ...
Royal Soc Chemistry2017

Investigating the Biological Mechanisms underlying the Initiation of Autoimmunity against Beta Cell Antigens in Type 1 Diabetes

Chiara Cianciaruso

Type 1 diabetes (T1D) is an autoimmune disease characterized by circulating autoantibodies, lymphocytic infiltration of pancreatic islets of Langerhans, and cell-specific destruction of beta cells, leading to insulin deficiency and symptomatic hyperglycemi ...
EPFL2017

An electrochemical sensor for quantitative analysis of Rhesus D antibodies in blood

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo, Tugba Kilic

The Hemolytic Disease of the Fetus and Newborn (HDFN), if untreated, can have severe consequences on baby’s health, eventually causing death. Prevention and diagnosis of pregnancies at risk of HDFN consists in quantitative analysis in hospital every 2-4 we ...
IEEE2017

Automated tracking of temporal displacements of a red blood cell obtained by time-lapse digital holographic microscopy

Benjamin Rappaz

Red blood cell (RBC) phase images that are numerically reconstructed by digital holographic microscopy (DHM) can describe the cell structure and dynamics information beneficial for a quantitative analysis of RBCs. However, RBCs investigated with time-lapse ...
Optical Soc Amer2016

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