Concept

Dicloxacillin

Publications associées (8)

Characteristics of Upward Lightning Flashes

In addition to the general aims of lightning research such as lightning physics and meteorology, the study of upward lightning is of particular importance in protection of tall objects such as wind turbines and telecommunication towers. It also helps us in ...

EPFL2018

Selecting the best AOP for isoxazolyl penicillins degradation as a function of water characteristics: Effects of pH, chemical nature of additives and pollutant concentration

César Pulgarin, Paola Villegas Guzman

To provide new insights toward the selection of the most suitable AOP for isoxazolyl penicillins elimination, the degradation of dicloxacillin, a isoxazolyl penicillin model, was studied using different advanced oxidation processes (AOPs): ultrasound (US), ...

Elsevier2017

Improving Bicyclic Peptide Phage Display and Development of Sortase A Inhibitors

Inmaculada Rentero Rebollo

Bicyclic peptide ligands are promising molecules for the development of new therapeutics. They combine advantages from large protein therapeutics and small molecule drugs. Large combinatorial libraries of bicyclic peptides can be generated and screened by ...

EPFL2014

On the active site of mononuclear B1 metallo beta-lactamases: a computational study

Matteo Dal Peraro, Paolo Carloni

Metallo-beta-lactamases (M beta Ls) are Zn(II)-based bacterial enzymes that hydrolyze beta-lactam antibiotics, hampering their beneficial effects. In the most relevant subclass (B1), X-ray crystallography studies on the enzyme from point to either two zinc ...

2012

Transformation of beta-Lactam Antibacterial Agents during Aqueous Ozonation: Reaction Pathways and Quantitative Bioassay of Biologically-Active Oxidation Products

Urs von Gunten

Reactions of ozone (O-3) with the beta-lactam antibiotics penicillin G (PG) and cephalexin (CP) have previously been found to yield products retaining antibacterial activities. These products are unequivocally identified here as the stereoisomeric (R)-sulf ...

2010

Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis

Stewart Cole, Claudia Sala

Comparative genomics with Staphylococcus aureus suggested the existence of a regulatory system governing beta-lactamase (BlaC) production in Mycobacterium tuberculosis. The crystal structure of Rv1846c, a winged helix regulator of previously unknown functi ...

2009

Miniaturised flow-through cell with integrated capacitive EIS sensor fabricated at wafer level using Si and SU-8 technologies

Eight different miniaturised flow-through cell configurations with integrated capacitive EIS (electrolyte-insulator-semiconductor) structures have been fabricated at wafer level. The EIS structures have been prepared by means of Si technique (electron-beam ...

2005

Structural determinants and hydrogen-bond network of the mononuclear zinc(II)-beta-lactamase active site

Matteo Dal Peraro

Zinc(II)-beta-lactamases are among the latest generation of antibiotic-resistant enzymes developed by bacteria against beta-lactams. Here we have used density functional theory to provide the full structure of the catalytic site from Bacillus cereus mononu ...

2002

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