Concept
Méningococcie
Publications associées (12)
CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection
Ludovic Pierre Gustave Keiser, Laura Desban
The pathogenic bacterium Streptococcus pneumoniae (S. pneumoniae) can invade the cerebrospinal fluid (CSF) and cause meningitis with devastating consequences. Whether and how sensory cells in the central nervous system (CNS) become activated during bacteri ...
CELL PRESS2023Simultaneous membrane and RNA binding by Tick-Borne Encephalitis Virus capsid protein
Tick-borne encephalitis virus is an enveloped, pathogenic, RNA virus in the family Flaviviridae, genus Flavivirus. Viral particles are formed when the nucleocapsid, consisting of an RNA genome and multiple copies of the capsid protein, buds through the end ...
PUBLIC LIBRARY SCIENCE2023Cecropins contribute to Drosophila host defense against a subset of fungal and Gram-negative bacterial infection
Bruno Lemaitre, Mark Austin Hanson, Alexia Laurie Carboni
Cecropins are small helical secreted peptides with antimicrobial activity that are widely distributed among insects. Genes encoding Cecropins are strongly induced upon infection, pointing to their role in host defense. In Drosophila, four cecropin genes cl ...
OXFORD UNIV PRESS INC2022Seasonal and spatial variability of antibiotic resistance genes and Class I integrons in the rivers of the Mekong delta, Vietnam
Pierre Rossi, Florian Frédéric Vincent Breider, Emmanuelle Rohrbach
Aquaculture activities are steadily expanding in Vietnam, covering an estimated 700,000 ha, with 89% of these culture ponds located in the Mekong Delta. Since 2009, large-scale bacterial epidemics have spread in response to this intensive cultivation. Anti ...
2021Keep calm and carry on vaccinating: Is anti-vaccination sentiment contributing to declining vaccine coverage in England?
Background: In England, coverage for childhood vaccines have decreased since 2012/13 in the context of an increasingly visible anti-vaccination discourse. We determined whether anti-vaccination sentiment is the likely cause of this decline in coverage. Met ...
2020Rapid and Digital Detection of Inflammatory Biomarkers Enabled by a Novel Portable Nanoplasmonic Imager
Hatice Altug, Filiz Yesilköy, Alexander Belushkin
New point-of-care diagnostic devices are urgently needed for rapid and accurate diagnosis, particularly in the management of life-threatening infections and sepsis, where immediate treatment is key. Sepsis is a critical condition caused by systemic respons ...
WILEY-V C H VERLAG GMBH2019Exome Sequencing Reveals Primary Immunodeficiencies in Children with Community-Acquired Pseudomonas aeruginosa Sepsis
Jacques Fellay, Istvan Bartha, Samira Asgari, Christoph Berger, Richard Wong
One out of three pediatric sepsis deaths in high income countries occur in previously healthy children. Primary immunodeficiencies (PIDs) have been postulated to underlie fulminant sepsis, but this concept remains to be confirmed in clinical practice. Pseu ...
Frontiers Media Sa2016Structure of viral membrane-penetrating machines by electron cryo-microscopy and tomography
My PhD thesis aims to obtain the structure of several bacteriophages, including so-called “jumbo” phages, using the electron cryo-microscopy (cryo-EM) and to study the structural transformation of these viruses as they attach and infect the host cell. We a ...
EPFL2015Likelihood Estimation for the INAR(p) Model by Saddlepoint Approximation
Saddlepoint techniques have been used successfully in many applications, owing to the high accuracy with which they can approximate intractable densities and tail probabilities. This article concerns their use for the estimation of high-order integer-value ...
American Statistical Association2015H-1, C-13 and N-15 assignment of the C-terminal domain of GNA2132 from Neisseria meningitidis
GNA2132 (Genome-derived Neisseria Antigen 2132) is a surface-exposed lipoprotein discovered by reverse vaccinology and expressed by genetically diverse Neisseria meningitidis strains (Pizza et al. 2000). The protein induces bactericidal antibodies against ...
2010