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A novel MR-guided brain therapy device operating at 1 MHz has been designed and constructed. The system has been installed and tested in a clinical 1.5 T Philips Achieva MRI. Skull bone distortions induced on the ultrasonic beam are corrected using the con ...
Complex brain diseases and neurological disorders in human generally result from the disturbance of multiple genes and signaling pathways. These disturbances may derive from mutations, deletions, translocations or rearrangements of specific gene(s). Howeve ...
Neurological disorders of body representation have for a long time suggested the importance of multisensory processing of bodily signals for self-consciousness. One such group of disorders--illusory own body perceptions affecting the entire body--has been ...
BACKGROUND: Reports of able-bodied participants with the persisting desire for limb amputation raise legal and ethical questions that are partly due to insufficient empirical knowledge about the condition. Here, we searched for potential neurological mecha ...
When and where is visual motion processed in the human brain? This question is highly relevant considering the importance of motion for our perception of the dynamical world surrounding us. In the present work we studied motion processing, firstly through ...
Artificial stimulation of the peripheral vestibular system has been shown to improve ownership of body parts in neurological patients, suggesting vestibular contributions to bodily self-consciousness. Here, we investigated whether galvanic vestibular stimu ...
In the present work, we report repeated out-of-body experiences (OBEs) in a patient with tetraplegia and severe somatosensory loss due to multiple sclerosis and predominant involvement of the cervical spinal cord. OBEs were experienced on a daily basis and ...
Neurological patients with impaired upper limbs often receive arm therapy to restore or relearn lost motor functions. During the last years robotic devices were developed to assist the patient during the training. In daily life the diversity of movements i ...
Recent philosophical and neuroscientific theories converge on the assumption that the basic foundations of self-consciousness lie in those brain systems that represent the body. Neurological cases in which this basic bodily self-consciousness is disturbed ...
The NAD-dependent deacetylase Sir2 was initially identified as a mediator of replicative lifespan in budding yeast and was subsequently shown to modulate longevity in worms and flies. Its mammalian homologue, SIRT1, seems to have evolved complex systemic r ...
