Concept
Brevetabilité du vivant
Publications associées (7)
Analysis of cellular and drug action mechanisms in the malaria parasites using systems biology approaches
Malaria puts at risk of infection half of the world population and still kills around half a million people every year. The rapid and worrisome rise of drug-resistant malaria parasites hinders the treatment of malaria and calls for a global collaboration t ...
EPFL2018Large Scale Dynamic Models of Metabolism as a Tool for Analysis and Design of Metabolic Engineering and Synthetic Biology Strategies
Vassily Hatzimanikatis, Ljubisa Miskovic, Georgios Fengos
Large-scale dynamic models of metabolism remain an overarching ambition of efforts that aim to analyze and explain complex behavior of living entities. However, intrinsic nonlinearity of dynamics of living organisms and structural and quantitative uncertai ...
2016Reversible supramolecular modification of surfaces
Enzymes are biocatalysts widely used in a large number of industrial biotech processes as they offer clear advantages over their chemical counterparts. Indeed, enzymes often show high substrate selectivity along with elevated turnover rates. Enzymatic cata ...
EPFL2015Proof of concept for microarray-based detection of DNA-binding oncogenes in cell extracts
The function of DNA-binding proteins is controlled not just by their abundance, but mainly at the level of their activity in terms of their interactions with DNA and protein targets. Moreover, the affinity of such transcription factors to their target sequ ...
2005Cancer vaccine design: a novel bacterial adjuvant for peptide-specific CTL induction
The recent identification of tumor Ags as potential vaccines has prompted the search for efficient adjuvants and delivery systems, especially in the case of peptide-based vaccination protocols. Here, we investigated the adjuvant potential of the recombinan ...
2001