Concept

Ménagère (couverts)

Publications associées (4)

Innovative, Non-stirred Bioreactors in Scales from Milliliters up to 1000 Liters for Suspension Cultures of Cells using Disposable Bags and Containers – A Swiss Contribution

Florian Maria Wurm, David Hacker, Lucia Baldi Unser, Mathieu Benjamin Stettler, Stéphanie Tissot, Xiaowei Zhang, Gilles Broccard

Innovative mixing principles in bioreactors, for example using the rocking of a platform to induce a backwards and forwards 'wave' , or using orbital shaking to generate a 'wave' that runs round in a cylindrical container, have proved to be successful for ...
Schweizerische Chemische Gesellschaft2010

Use of Orbital Shaken Disposable Bioreactors for Mammalian Cell Cultures from the Milliliter-Scale to the 1,000-Liter Scale

Alfio Quarteroni, Florian Maria Wurm, David Hacker, Mathieu Benjamin Stettler, Xi Zhang

Driven by the commercial success of recombinant biopharmaceuticals, there is an increasing demand for novel mammalian cell culture bioreactor systems for the rapid production of biologicals that require mammalian protein processing. Recently, orbitally sha ...
2009

Microfluidic system based on thermoexpandable polymer for on chip blood coagulation testing

Philippe Renaud, Lynda Metref, Raphaël Goetschmann, François Bianchi

This paper describes a simple system for the actuation of a biological fluid through micro-channels with a thermoactivated polymer actuator. This system is of interest for the development of single-use diagnostic test-strips since the actuation of the samp ...
2009

Bioreactor processes based on disposable materials for the production of recombinant proteins from mammalian cells

Mathieu Benjamin Stettler

The objective of industrial cell culture technology is to produce high value-added therapeutic proteins that are well suited for the treatment of infectious diseases, cancer, and autoimmune diseases. Nowadays, an important focus is the reduction of the tim ...
EPFL2007

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