Concept

Traitement de la douleur

Publications associées (64)

During capsaicin-induced central sensitization, brush allodynia is associated with baseline warmth sensitivity, whereas mechanical hyperalgesia is associated with painful mechanical sensibility, anxiety and somatization

Background Mechanical hyperalgesia and allodynia incidence varies considerably amongst neuropathic pain patients. This study explored whether sensory or psychological factors associate with mechanical hyperalgesia and brush allodynia in a human experimenta ...

WILEY2021

Enhancing analgesic spinal cord stimulation for chronic pain with personalized immersive virtual reality

Olaf Blanke, Bruno Herbelin, Andrea Serino, Giulio Rognini, Marco Solcà, Robin Mange, Pavo Orepic

Spinal cord stimulation (SCS) is an approved treatment for truncal and limb neuropathic pain. However, pain relief is often suboptimal and SCS efficacy may reduce over time, requiring sometimes the addition of other pain therapies, stimulator revision, or ...

2020

The outcomes of a second and third Gamma Knife radiosurgery for recurrent essential glossopharyngeal neuralgia

Constantin Tuleasca, Anne Donnet

Introduction Gamma Knife radiosurgery (GKR) is a minimally invasive surgical option for drug-resistant essential glossopharyngeal neuralgia (GPN). The authors reviewed pain outcomes and complications in GPN patients who underwent a second or a third GKR fo ...

2020

Studying the interactions between electro-magnetic elds and biological tissue

Laurine Kolly

Drug delivery systems (DDS) were engineered to overcome the drawbacks of more common methods such as oral pills and intravenous injections. Implantable capsules that release anesthetic drugs locally for pain management after Total Knee Arthroplasty (TKA) a ...

2020

Behavioral and neurophysiological evidence for altered interoceptive bodily processing in chronic pain

Olaf Blanke, Fosco Bernasconi, Hyeongdong Park, Marco Solcà

Whereas impaired multisensory processing of bodily stimuli and distorted body representation are well-established in various chronic pain disorders, such research has focused on exteroceptive bodily cues and neglected bodily signals from the inside of the ...

2020

Cognitive neuroprosthetics for investigating and restoring body perception

Marco Solcà

Our brain constantly receives and integrates a flow of multisensory bodily inputs that are responsible for the way our body is represented and consciously experienced. However, in some pathological conditions, patients might experience altered perceptions ...

EPFL2019

The Adapted Lifestyle-Integrated Functional Exercise Program for Preventing Functional Decline in Young Seniors: Development and Initial Evaluation

Wei Zhang

Background: The Lifestyle-integrated Functional Exercise (LiFE) program is an intervention integrating balance and strength activities into daily life, effective at reducing falls in at-risk people >= 70 years. There is potential for LiFE to be adapted to ...

KARGER2019

Stereotactic radiosurgery for trigeminal neuralgia: a systematic review

Constantin Tuleasca

OBJECTIVES The aims of this systematic review are to provide an objective summary of the published literature specific to the treatment of classical trigeminal neuralgia with stereotactic radiosurgery (RS) and to develop consensus guideline recommendations ...

AMER ASSOC NEUROLOGICAL SURGEONS2019

Gas-phase structures reflect the pain-relief potency of enkephalin peptides

Vladimir Kopysov, Aleksandr Pereverzev

We use cold ion spectroscopy and quantum-chemical computations to solve the structures of opioid peptides enkephalins in the gas phase. The derived structural parameters clearly correlate with the known pharmacological efficiency of the studied drugs, sugg ...

2019

Heartbeat-enhanced immersive virtual reality to treat complex regional pain syndrome

Olaf Blanke, Bruno Herbelin, Andrea Serino, Roberta Ronchi, Marco Solcà, Javier Bello Ruiz, Thomas Schmidlin

OBJECTIVES: To develop and test a new immersive digital technology for complex regional pain syndrome (CRPS) that combines principles from mirror therapy and immersive virtual reality and the latest research from multisensory body processing. METHODS: In t ...

2018

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