Publications associées (19)

X-ray phase contrast imaging of the bone-cartilage interface

Synoyial joints articulate in a lubricating environment, the system providing for smooth articulation. The articular cartilage overlying the bone consists of a network of collagen fibres. This network is essential to cartilage integrity, suffering damage i ...
2010

mu-PIXE and SAXS studies at the bone-cartilage interface

Micro Proton Induced X-ray Emission (mu-PIXE) analysis has been employed herein in investigating and quantifying the distribution of a number of essential elements in thin human diseased articular cartilage sections affected by osteoarthritis (OA). Various ...
2010

Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation

Denis Duboule

The molecular mechanisms that govern bone and joint formation are complex, involving an integrated network of signaling pathways and gene regulators. We investigated the role of Hox genes, which are known to specify individual segments of the skeleton, in ...
American Society for Clinical Investigation2010

3D strain map of axially loaded mouse tibia: a numerical analysis validated by experimental measurements

Dominique Pioletti, Alexandre Terrier, Vincent Stadelmann, Francesco Merlini, Vincent Forster, Jean Hocké, Jensen Verhelle

A combined experimental/numerical study was performed to calculate the 3D octahedral shear strain map in a mouse tibia loaded axially. This study is motivated by the fact that the bone remodelling analysis, in this in vivo mouse model should be performed a ...
2009

Effect of calcification on agarose gel stiffness and integration strength with Bone

Jérôme Hollenstein

The zone of calcified cartilage (ZCC) is critical for the normal attachment of articular cartilage to bone as well as to the biomimetic bioengineering of osteochondral tissue constructs. However, relatively few osteochondral tissue engineering approaches h ...
2009

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