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Vestibular modulation of peripersonal space boundaries

Olaf Blanke, Christian Pfeiffer, Andrea Serino, Jean-Paul Noel

Human-environment interactions are mediated through the body and occur within the peripersonal space (PPS), the space immediately adjacent to and surrounding the body. The PPS is taken to be a critical interface between the body and the environment, and in ...

2018

Model-based reinforcement learning and navigation in animals and machines

Dane Sterling Corneil

For decades, neuroscientists and psychologists have observed that animal performance on spatial navigation tasks suggests an internal learned map of the environment. More recently, map-based (or model-based) reinforcement learning has become a highly activ ...

EPFL2018

Artificial spatiotemporal touch inputs reveal complementary decoding in neocortical neurons

Silvestro Micera

Investigations of the mechanisms of touch perception and decoding has been hampered by difficulties in achieving invariant patterns of skin sensor activation. To obtain reproducible spatiotemporal patterns of activation of sensory afferents, we used an art ...

Nature Research2017

A 16-Channel 1.1mm2 Implantable Seizure Control SoC with Sub-μW/Channel Consumption and Closed-Loop Stimulation in 0.18μm CMOS

Alexandre Schmid, Mahsa Shoaran, Yusuf Leblebici, Amirhossein Shahshahani, Masoud Shahshahani

We present a 16-channel seizure detection system-on-chip (SoC) with 0.92μW/channel power dissipation in a total area of 1.1mm² including a closed-loop neural stimulator. A set of four features are extracted from the spatially filtered neural data to achiev ...

IEEE2016

New Developments and Applications of the MP2RAGE Sequence - Focusing the Contrast and High Spatial Resolution R1 Mapping

Rolf Gruetter, José Pedro Rebelo Ferreira Marques

MR structural T1-weighted imaging using high field systems (>3T) is severely hampered by the existing large transmit field inhomogeneities. New sequences have been developed to better cope with such nuisances. In this work we show the potential of a recent ...

Public Library of Science2013

Rhythmic Modulation of Theta Oscillations Supports Encoding of Spatial and Behavioral Information in the Rat Hippocampus

Oscillatory patterns of activity in various frequency ranges are ubiquitously expressed in cortical circuits. While recent studies in humans emphasized rhythmic modulations of neuronal oscillations ("second-order" rhythms), their potential involvement in i ...

Elsevier2012

Complexity and performance in simple neuron models

Wulfram Gerstner, Richard Naud, Skander Mensi

The ability of simple mathematical models to predict the activity of single neurons is important for computational neuroscience. In neurons, stimulated by a time-dependent current or conductance, we want to predict precisely the timing of spikes and the su ...

2010

Is there a geometric module for spatial orientation? Insights from a rodent navigation model

Wulfram Gerstner, Ricardo Andres Chavarriaga Lozano, Thomas Strösslin, Angelo Arleo

Modern psychological theories of spatial cognition postulate the existence of a geometric module for reorientation. This concept is derived from experimental data showing that in rectangular arenas with distinct landmarks in the corners, disoriented rats o ...

American Psychological Association2009

Expression of brain-derived neurotrophic factor is not modulated by chronic mild stress in the rat hippocampus and amygdala

Pierre Magistretti, Jean-Luc Martin, Igor Allaman

Accumulating evidence supports a role for brain-derived neurotrophic factor (BDNF) in depression. However, most of these studies have been performed in animal models that have a low face validity with regard to the human disease. Here, we examined the regu ...

2009

AMPA receptor imaging by infrared scanning near-field optical microscopy

Giorgio Margaritondo, Kai Johnsson, Harald Hirling, Johanna Generosi, Michel Kropf

Infrared scanning near-field optical microscopy is used to detect AMPA-type glutamate receptor clusters in hippocampal neuron cells. AMPA's GluR2-subunits were marked with the fluorophore Alexa488 and high-resolution micrographs were taken at 6.25 µm wavel ...

Wiley2008

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